Protein Info for H281DRAFT_06367 in Paraburkholderia bryophila 376MFSha3.1

Annotation: pilus assembly protein CpaE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 403 PF13614: AAA_31" amino acids 133 to 282 (150 residues), 39.6 bits, see alignment E=7.8e-14 PF01656: CbiA" amino acids 135 to 335 (201 residues), 27 bits, see alignment E=5.9e-10

Best Hits

KEGG orthology group: K02282, pilus assembly protein CpaE (inferred from 93% identity to bug:BC1001_5122)

Predicted SEED Role

"Type II/IV secretion system ATPase TadZ/CpaE, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (403 amino acids)

>H281DRAFT_06367 pilus assembly protein CpaE (Paraburkholderia bryophila 376MFSha3.1)
MINILINSEHTGRMSEVVRFVTDCGNCTTTRMQGAPSTLLERGDSLDAFDVLIIDAASIE
RAELDSVNLLVHRYPRLTCLLLLPQTSPDTLIAAMRAGVRDVLNWPLDARALGAAVQRAM
APHADEARQETHMVSFISCKGGAGTSLIAANVGHAIATLHGKRVLLVDLNQMFADAAFLV
SDQEPPSTLPQICAQIERIDAAFLDASLTHVTPGFHVLAGAGDPLKALDIHEEQLEWILG
VAAPRYDVVLFDLGQSINALSIVALDRSAEIHLVLQASMPYVRAGRRLQEMLVSLAYSPD
RMRLLLNRHRRHDERAASALEQVLGRRPSHLIADDPQAAAEAVNLGEPLLKNARNSALTR
SIQALAQSIVNQSTGVVPQKKRDDPLLARLFGRSATQRQSTAS