Protein Info for H281DRAFT_05305 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 645 transmembrane" amino acids 24 to 43 (20 residues), see Phobius details amino acids 49 to 70 (22 residues), see Phobius details amino acids 83 to 106 (24 residues), see Phobius details amino acids 113 to 130 (18 residues), see Phobius details amino acids 137 to 157 (21 residues), see Phobius details amino acids 163 to 182 (20 residues), see Phobius details PF00512: HisKA" amino acids 217 to 283 (67 residues), 48.5 bits, see alignment E=1.1e-16 PF02518: HATPase_c" amino acids 328 to 435 (108 residues), 95 bits, see alignment E=6e-31 PF00072: Response_reg" amino acids 463 to 578 (116 residues), 37.9 bits, see alignment E=2.7e-13

Best Hits

KEGG orthology group: None (inferred from 89% identity to bug:BC1001_5584)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MGZ8 at UniProt or InterPro

Protein Sequence (645 amino acids)

>H281DRAFT_05305 Signal transduction histidine kinase (Paraburkholderia bryophila 376MFSha3.1)
MRADPIQRAIDEDLVRVLYAQDPIAFFSHWFSIAVLVAIYWPAIPSPPLFIACFGFYAAA
NCAGLALWICNRRYPHLVSPRGWINLHAVRGVLLYSAPGIAIWFAFQSPQSDLPLLHTVM
LVTLAAGVFMSNGFDMLNFATAIPFLLFPSILLHFGTHTFDRTILAIVLAFFFCAINVYA
LSYRKLFQQVVQARVDQQYLAESLAMQKHVAEEASLAKTRFFAAASHDLRQPLHAIGLLA
ASLNDPAATPAQHAKTAEHIVYNVEALNQLFNQVLDLARLESGVTQVIRLHFRLSELFER
VGSQYRPQAAAKGLALRIAPTSMVVHDDPVLLERVLSNLLSNAVRYTEEGAIWLGVRRAG
RTTGGYIEVRDSGIGIPAEEHERIFEEFYQVANPQRDARQGHGLGLPTVKRLVGMLGGEL
QLRSAPGRGSVFRFPVQEGDASAIVASLNEAGAGGPSAQGRQVLCIDDEPSILEGLSALL
GRWGCTVRGARDEAAALAALADGFVPDAVLCDYQLANHRTGAQALTAVRSMLAHAGHEGV
VTLLITGDMASAELAALALQGIPVLHKPVTAARLRRTLEMLWQQAELDKGHQGAASESPA
GHSVDAGGEGTVLSEETGGAQATMPQGRAGVEVRHRPQSASQQEG