Protein Info for H281DRAFT_05302 in Paraburkholderia bryophila 376MFSha3.1

Annotation: FAD/FMN-containing dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 PF01565: FAD_binding_4" amino acids 58 to 195 (138 residues), 120.3 bits, see alignment E=5.2e-39 PF02913: FAD-oxidase_C" amino acids 235 to 476 (242 residues), 152 bits, see alignment E=2.5e-48

Best Hits

KEGG orthology group: None (inferred from 91% identity to bgf:BC1003_5675)

Predicted SEED Role

"D-2-hydroxyglutarate dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MIU6 at UniProt or InterPro

Protein Sequence (477 amino acids)

>H281DRAFT_05302 FAD/FMN-containing dehydrogenase (Paraburkholderia bryophila 376MFSha3.1)
MTDNSNANPPLSTAAPAAPLAATLDALRAALGDEAVRVGDEIGERALTDWTRHAPTRPAA
LLLPRSTEDVARALAICHAACQPVVPQGGMTGLAGGAIARANDIALSLERLTGIEEIDAA
SATLTVRAGTTLQTAQEAAAQAGFELALDLGARGSCQIGGNLATNAGGNRVIQSGTARDQ
VLGLEVVLANGDVLTSLGKMVKNNTGYDLKHWFIGSEGTLGIITRAVLRLHPQRAARHTA
LVALDGYDAAVNLLRRLSTRFGNDIGAFEIMWPDFYEFGVKLTGARSPFNGSHPLYALIE
HASFDASDNGERFSAALTDALEQGAIRDAVIAQSVADARALWAIRECTAEFPVRLDAINF
DVSLPISVIGEFVERCRSALNERWPGNESYFFGHIGDSNLHVTVDGHSIPGVDHHAVYAF
VYEMLGPLHGSVSAEHGIGLLKREFLPISRSPAELAAMAAIKHALDPHGILNPGKLF