Protein Info for H281DRAFT_04137 in Paraburkholderia bryophila 376MFSha3.1

Annotation: cyclopropane-fatty-acyl-phospholipid synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 PF02353: CMAS" amino acids 108 to 380 (273 residues), 344.8 bits, see alignment E=1.6e-106 PF01135: PCMT" amino acids 154 to 227 (74 residues), 20.9 bits, see alignment E=1.2e-07 PF08123: DOT1" amino acids 156 to 212 (57 residues), 25.4 bits, see alignment 4.3e-09 PF13489: Methyltransf_23" amino acids 158 to 278 (121 residues), 48.5 bits, see alignment E=3.8e-16 PF05175: MTS" amino acids 162 to 239 (78 residues), 23.2 bits, see alignment E=2.2e-08 PF13847: Methyltransf_31" amino acids 169 to 270 (102 residues), 31.6 bits, see alignment E=5.9e-11 PF08241: Methyltransf_11" amino acids 174 to 269 (96 residues), 47 bits, see alignment E=1.5e-15 PF13649: Methyltransf_25" amino acids 174 to 267 (94 residues), 58.6 bits, see alignment E=3.7e-19 PF08242: Methyltransf_12" amino acids 174 to 268 (95 residues), 44.1 bits, see alignment E=1.3e-14

Best Hits

Swiss-Prot: 47% identical to FAMT_PSEPU: Probable fatty acid methyltransferase from Pseudomonas putida

KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 98% identity to bug:BC1001_2873)

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)" (EC 2.1.1.79)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.79

Use Curated BLAST to search for 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MDV3 at UniProt or InterPro

Protein Sequence (404 amino acids)

>H281DRAFT_04137 cyclopropane-fatty-acyl-phospholipid synthase (Paraburkholderia bryophila 376MFSha3.1)
MFWEKKLAQWVEEVKTKADLPARLVLWDGQQHDFGRFAAPQVTLHVKSATALPYLLEPSL
DNLGEAYVKGKIDIEGKLSDIINVGYQLARNTVTSASKLARMRRYFQHSKASDRKAIQYH
YDVSNEFYKLWLDENMVYSCAYFENGNEDLATAQIKKIDHILTKIQLQPGQRLLDIGCGW
GALVLRAAQKFGAQCVGVTLSQNQFDLATARVKAAGLENQIEIRLQDYRDVEGQFDRITS
VGMFEHVGRKNLPGYFRKMHDLLADDGVAMNHGITSSDSDSGETALGGGEFIDRYVFPDG
ELPHISLALESMQRGGLEAVDVESLRRHYAHTLDIWAENFEAHAEEARKLVDDEKFRIWR
VYLAGCAYAFENDDVSIYQVVCRKAGRSAKTLPWSRRYMYEKPL