Protein Info for H281DRAFT_03817 in Paraburkholderia bryophila 376MFSha3.1

Annotation: drug resistance transporter, EmrB/QacA subfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 35 to 53 (19 residues), see Phobius details amino acids 65 to 91 (27 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 124 to 145 (22 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details amino acids 215 to 234 (20 residues), see Phobius details amino acids 255 to 278 (24 residues), see Phobius details amino acids 290 to 309 (20 residues), see Phobius details amino acids 321 to 339 (19 residues), see Phobius details amino acids 346 to 369 (24 residues), see Phobius details amino acids 390 to 409 (20 residues), see Phobius details amino acids 472 to 491 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 5 to 163 (159 residues), 28.2 bits, see alignment E=1.4e-10 PF07690: MFS_1" amino acids 5 to 398 (394 residues), 184.3 bits, see alignment E=4.7e-58 PF06609: TRI12" amino acids 18 to 418 (401 residues), 50.3 bits, see alignment E=2.1e-17

Best Hits

KEGG orthology group: None (inferred from 97% identity to bug:BC1001_4545)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MNM9 at UniProt or InterPro

Protein Sequence (502 amino acids)

>H281DRAFT_03817 drug resistance transporter, EmrB/QacA subfamily (Paraburkholderia bryophila 376MFSha3.1)
MLGIGLVNMLVALDQTVVSTALPSIVAELHGFEYYAWIASAYLLASVVTVPVFGRLGDYF
GRKRFVIAAVITFTVASVLCGVANNMLFLVIARGLQGVGGGMMVGTAFASIPDLFPDPRA
RVRWQVVMAAAYGIGTAAGPSLGGWMSEHLGWRSTFLINLPVGAAALYFIWVHLPSFQRP
HDGEVKIDWLGAGLVAAVLGGLQAFIEAVPKDGLTAGNITLAVCVIVGAVALYVCEKRAT
HPIIPLDLFKDSQLVTLFTLGMLSGFVMFSLIFFAPLLLQGGFGLSPQQAGLLATPIAAC
IALGSLLNTRIVIHMKKPTRILSIGFALLLFASIGLAFANPDTPHLWIELPMAAVGIGLG
FILNNLNVFGQEIAGRERFGITTALLQSTRMVGGMLGTSIVATVVQHHYRDVVTRTMSVL
GEPTATQWRPRFVDLRILIDEASRLKLIADMKPSGLNTLALIDTARDALVQSIHIGVWLT
AVAALAAALLVQRISHVVFRRG