Protein Info for H281DRAFT_03102 in Paraburkholderia bryophila 376MFSha3.1

Annotation: cyclopropane-fatty-acyl-phospholipid synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 180 to 199 (20 residues), see Phobius details PF02353: CMAS" amino acids 116 to 392 (277 residues), 314.6 bits, see alignment E=1.7e-97 PF13489: Methyltransf_23" amino acids 163 to 284 (122 residues), 37.6 bits, see alignment E=5.7e-13 PF13847: Methyltransf_31" amino acids 175 to 284 (110 residues), 31.7 bits, see alignment E=3.8e-11 PF08242: Methyltransf_12" amino acids 181 to 277 (97 residues), 34.1 bits, see alignment E=1.2e-11 PF08241: Methyltransf_11" amino acids 181 to 278 (98 residues), 42.7 bits, see alignment E=2.3e-14 PF13649: Methyltransf_25" amino acids 181 to 276 (96 residues), 54.1 bits, see alignment E=6.4e-18

Best Hits

KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 89% identity to bug:BC1001_4226)

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)" (EC 2.1.1.79)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.79

Use Curated BLAST to search for 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>H281DRAFT_03102 cyclopropane-fatty-acyl-phospholipid synthase (Paraburkholderia bryophila 376MFSha3.1)
MTLWSLLRSPAEQQIAGMPVPCSVALPDGQRIGAREPRLSFEIRDTRALLHLTQGAIGRL
AEDYVEGRLEIDGSMHDLMAAAPALLRSDPTHETHGWLLDHVNRARRAIWERTHHSRAKD
AAQIQHHYDVSDDFYALWLDPLRVYSCAYFSSPDMSLADAQQAKLDHICRKLMLRSGERF
LDVGAGWGALLLWAAEYYGVAATGITLSRNQHAYVNRLIEQKGLQGRVTMLLQDYRDVDE
SAPFDKVASVGMCEHVGRLNLPAYFAKMRRLLRPGGLMMNHSITAGGADNAEVGGGMGDF
IDRYIFPGGQLVHVSVMMNAMTRGNLEPVDAECLRPHYAKTLWHWADALEAHLDQAREVL
GKDAEKIIRAYRLYLAGSAMGFERGWTSLFQILASRPAESVKADDGHAGRMPWAHSDYPF
NRTYMYARDRAIDRVNEVERANGGHEIR