Protein Info for H281DRAFT_02851 in Paraburkholderia bryophila 376MFSha3.1

Annotation: TIGR00659 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 44 to 66 (23 residues), see Phobius details amino acids 74 to 92 (19 residues), see Phobius details amino acids 103 to 128 (26 residues), see Phobius details amino acids 157 to 180 (24 residues), see Phobius details amino acids 192 to 209 (18 residues), see Phobius details amino acids 216 to 241 (26 residues), see Phobius details PF04172: LrgB" amino acids 25 to 238 (214 residues), 274.5 bits, see alignment E=2.6e-86

Best Hits

Swiss-Prot: 35% identical to YXAC_BACSU: Uncharacterized protein YxaC (yxaC) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 94% identity to bpy:Bphyt_5345)

Predicted SEED Role

"LrgA-associated membrane protein LrgB" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MKH9 at UniProt or InterPro

Protein Sequence (246 amino acids)

>H281DRAFT_02851 TIGR00659 family protein (Paraburkholderia bryophila 376MFSha3.1)
MTALPKLGALWVYLAASPLLGLTITLIAYLIAQTLYAKARFNPLANPVLIAVALLVALLE
ITGTPYATYFEGAQFVHFLLGPATVALALPLYRQWPKLRRFAFPLIGGLVAGSLTAILSA
VAVAALFGASHQTVASLAPKSATTPIAMAVASEIGGIPSLTAVLVISTGVFGAVFARAIL
NALKIAEPEVRGFALGVASHGIGTARAFQVSEQMGAFAGLGMGLNGVFTAFVVPVLMPLI
ARWIGA