Protein Info for Ga0059261_3965 in Sphingomonas koreensis DSMZ 15582

Annotation: formimidoylglutamate deiminase (EC 3.5.3.13)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 TIGR02022: formiminoglutamate deiminase" amino acids 3 to 446 (444 residues), 614.5 bits, see alignment E=5.7e-189 PF01979: Amidohydro_1" amino acids 46 to 419 (374 residues), 95.3 bits, see alignment E=2.3e-31

Best Hits

KEGG orthology group: None (inferred from 62% identity to sal:Sala_1687)

MetaCyc: 54% identical to formiminoglutamate deiminase subunit (Pseudomonas fluorescens)
Formimidoylglutamate deiminase. [EC: 3.5.3.13]

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WIA3 at UniProt or InterPro

Protein Sequence (447 amino acids)

>Ga0059261_3965 formimidoylglutamate deiminase (EC 3.5.3.13) (Sphingomonas koreensis DSMZ 15582)
MNLWFESALLENGWSERVRLTLADGQIETVEAGVDPEAGDERHFVALPGIPNVHSHAFQR
AMAGLAEARGRADDDFWSWRELMYRFVGRIGPEECEAIAALAYAEMLESGFTRVGEFHYL
HHTPGGGRYDDVAEMSGRIAAAAAATGIALTLLPVFYAHGGFGGQPAGTAQARFLNDVDG
FAALVERAGATLASDGVIGIAPHSLRAATPGELRALLAMADRGPVHIHIAEQVKEVADCV
AWSGKRPVRWLLDNMPVDARWTLVHATHVEPGEVAGIAASGAVAGLCPITEANLGDGVFP
AAEFMALGGMIGIGSDSNVRIDAAEELRLLEYGQRLTRRARNVLAGGDRPATGARMFAAA
VAGGGRSLGVETGLAAGRPADIVSLNRDDPAFAERKGDALVDSWVFASRAGVDCVWRGGA
KQVAGGRHRDRDAIEARYRVALNRLMA