Protein Info for Ga0059261_3901 in Sphingomonas koreensis DSMZ 15582

Annotation: K+ transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 622 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details transmembrane" amino acids 43 to 65 (23 residues), see Phobius details amino acids 95 to 112 (18 residues), see Phobius details amino acids 132 to 153 (22 residues), see Phobius details amino acids 165 to 186 (22 residues), see Phobius details amino acids 203 to 229 (27 residues), see Phobius details amino acids 242 to 264 (23 residues), see Phobius details amino acids 284 to 308 (25 residues), see Phobius details amino acids 333 to 354 (22 residues), see Phobius details amino acids 362 to 386 (25 residues), see Phobius details amino acids 393 to 413 (21 residues), see Phobius details amino acids 420 to 438 (19 residues), see Phobius details PF02705: K_trans" amino acids 6 to 540 (535 residues), 709.9 bits, see alignment E=9.8e-218

Best Hits

Swiss-Prot: 72% identical to KUP2_SPHWW: Probable potassium transport system protein kup 2 (kup2) from Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 75% identity to sjp:SJA_C1-17450)

MetaCyc: 46% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WI22 at UniProt or InterPro

Protein Sequence (622 amino acids)

>Ga0059261_3901 K+ transporter (Sphingomonas koreensis DSMZ 15582)
LWKLAVGAIGIVFGDIGTSPLYAFRETFSAAHHPEHPLPLDELHILGVISLMFWSMMVVV
TLKYVSIIMRADNKGEGGSLALLALINRSSGQKRWTAGIVLLGVFATALFYGDSMITPAV
SVLSAVEGLAVAAPAFSNWVLPIAIAILVILFSIQRTGTARVGAMFGPIMLTYFATIATL
GLISASQTPGVLWAFLPSYAFNFFVVDPFAAFLALGSVVLAVTGAEALYADMGHFGRKPI
RFSWLWFVLPALMCNYLGQGALLMRDATALQNPFYMLAPEYLRLPLVGIATMAAIIASQA
VITGAFSVTQQGIQLGFIPRLRITHTSASTAGQIYIPLINWALMIAIILLVLTFQTSSNL
TAAYGIAVTGAMLIDNFLIAVVLFTLWKWKKRYAIPLLALFFLVDLAYFTANLTKVPDGG
WFPLLAGVVIFTLLTTWAKGRRLMVERMRESAMPIKVFIQSAAGSAARVPGTAVFMTSTP
EGVPHALLHNLKHNKVLHERVILLTVKIADMPYVAEEARVKVDDLGQGFHRMLLYYGFMQ
EADVPGALKAVGACGGKCGGAFNMMDTSFFLSRQTLLPSERPGMRIWREKLFAWMLRNAE
SAMEFFRLPTNRVVELGSQVEI