Protein Info for Ga0059261_3256 in Sphingomonas koreensis DSMZ 15582

Annotation: glycine cleavage system T protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 PF01571: GCV_T" amino acids 19 to 272 (254 residues), 265.5 bits, see alignment E=4.2e-83 TIGR00528: glycine cleavage system T protein" amino acids 19 to 379 (361 residues), 332.8 bits, see alignment E=1.1e-103 PF08669: GCV_T_C" amino acids 301 to 378 (78 residues), 75 bits, see alignment E=3.6e-25

Best Hits

KEGG orthology group: K00605, aminomethyltransferase [EC: 2.1.2.10] (inferred from 57% identity to nar:Saro_1850)

Predicted SEED Role

"Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10)" in subsystem Glycine and Serine Utilization or Glycine cleavage system or Photorespiration (oxidative C2 cycle) (EC 2.1.2.10)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WG99 at UniProt or InterPro

Protein Sequence (389 amino acids)

>Ga0059261_3256 glycine cleavage system T protein (Sphingomonas koreensis DSMZ 15582)
MSDATQEPEIVEELALLPLDAWHRAKGGRMVPFAGYEMPVQYEGIMAEHLWVRESAGLFD
VSHMGQLFLSGDGLDAALEALIPADVAGVKVNGQKYSLLLAQNGGILDDLMFTRWDADNG
AHPGAAGLYMVVNGACKWDDIAHLREHLPDEIEINHMDEHALLALQGPKAVDALSRLVPG
VEGLIFMRGGRFDWNGTSLWISRSGYTGEDGFEISVEADKAAALAGALTAQPEVKPIGLG
ARDSLRLEADLPLYGHDLDTETTPIMAALNFAVASKRRREEANFPGAERILLEREQGAIQ
RRVGLIVEGRQPVREGALVLDDEGNEVGRVTSGGFAPTVQKPIAMAYVPTAMAEVGTRVT
LSQRGKIHHGEVVPMPFVPHNYVREGGPK