Protein Info for Ga0059261_3181 in Sphingomonas koreensis DSMZ 15582

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 618 transmembrane" amino acids 10 to 31 (22 residues), see Phobius details amino acids 178 to 200 (23 residues), see Phobius details PF05227: CHASE3" amino acids 38 to 173 (136 residues), 124.2 bits, see alignment E=5.8e-40 PF02518: HATPase_c" amino acids 356 to 476 (121 residues), 74.4 bits, see alignment E=1.5e-24 PF00072: Response_reg" amino acids 502 to 612 (111 residues), 61.1 bits, see alignment E=1.6e-20

Best Hits

Predicted SEED Role

"putative two-component sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WFZ8 at UniProt or InterPro

Protein Sequence (618 amino acids)

>Ga0059261_3181 Signal transduction histidine kinase (Sphingomonas koreensis DSMZ 15582)
MGEVRRDRGLIALIIGFAVIAVAVFGTLLLFKQQQSAQRMVVHTLRVQEQLSTIRSRLQD
AETGQRGYLVTRDPVYLQPYFDGRRQLAGDLAALRPMLADNPIQLAAARQLEQCAVARVE
RLSVGLTQARAGRFDHAAEVVRVGVGKTLMDRCRAIIGAMKAEESRLLTARSEALASWSS
WLTLWLIGGALMVFALAVYATRDARRRARAAIKMGQALLEANRKITDEAESRAAVEAQLR
QMQKMESIGQLTGGVAHDFNNMLAIVIGSLDMAKRRFESDPKKALEGIGNAMEGAERAAQ
LTARLLAFSRQQPLAPKALDANKLVGGMSELLRRTISENIRIETVLAGGLWPAFIDGAQL
ENAVLNLCVNARDAMPGGGRLTIETANTHLDDAYAAAHAEVLSGQYVMVSVTDTGTGMPP
EVIERAFDPFYTTKGVGKGTGLGLSQVFGFVKQSGGHVKIYSEPGVGTTVKLYLPRHFGE
AETPGVPLSPDALPRAKDDEIILVVEDEEGVRHMSVDALRELGYVVVQASDANQALTVLE
IQPRIDLLFTDIVMPDMNGRVLSDRAREARPGLKVLYTTGYTRNAIVHNGMLDHDVAFLA
KPFTVQQLALKVREVLDA