Protein Info for Ga0059261_3070 in Sphingomonas koreensis DSMZ 15582

Annotation: Type IV secretory pathway, VirD4 components

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 674 transmembrane" amino acids 6 to 31 (26 residues), see Phobius details amino acids 43 to 63 (21 residues), see Phobius details amino acids 75 to 96 (22 residues), see Phobius details PF02534: T4SS-DNA_transf" amino acids 111 to 559 (449 residues), 347.5 bits, see alignment E=2e-107 PF10412: TrwB_AAD_bind" amino acids 196 to 546 (351 residues), 98.9 bits, see alignment E=4.7e-32 PF12696: TraG-D_C" amino acids 408 to 528 (121 residues), 100.1 bits, see alignment E=1.4e-32

Best Hits

KEGG orthology group: K03205, type IV secretion system protein VirD4 (inferred from 76% identity to sch:Sphch_2733)

Predicted SEED Role

"Type IV secretion system protein VirD4" in subsystem Type 4 secretion and conjugative transfer or pVir Plasmid of Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6JFK0 at UniProt or InterPro

Protein Sequence (674 amino acids)

>Ga0059261_3070 Type IV secretory pathway, VirD4 components (Sphingomonas koreensis DSMZ 15582)
VTPTKLLIGQILIVFGLVIAGLWAATQWAAAMLAYQPELGRPWLIVGDVPVYRPWALFSW
WYHYDAYAPHVFDKAGMLAGASGFLGCGAAIAGSLWRARQRSNVTTYGSARWAKPGEIER
AGLYRDRGVLLGRLGGQYLRHDGPEHVMAFAPTRSGKGVGLVVPTLLSWTGSTVVHDIKG
ENWTLTAGWRSRFSHCLLFNPTDPRSARYNPLLEVRRGADEVRDVQNIADILVDPEGALE
RRNHWEKTSHALLVGAILHILYAEEEKTLARVATFLSDPQRSFVATLRRMMSTNHLGTPE
TPRVHPVIASAARELLNKSENERSGVLSTAMSFLGIYRDPTVAEVTSRCDWRIADLIDGE
RPVSLYLVIPPSDISRTKPLVRLVLNQIGRRLTERLEQRDATTRRHQLLMMLDEFPALGR
LDFFETSLAFMAGYGIRAFLIAQSLNQIEKAYGEHNSILDNCHVRVAFATNDERTAKRIS
DALGTATEQRAMRNYAGHRLAPWLAHVMVSRQETARALLTPGEVMQLPATDELVLLSGLA
PVRATKLRYFEDRNFSGRVQPAPVLADGVYGDRPRQRSNDWGRFARFPDARLELAADLTD
AGDDGGMQQQRHPGLAQEGTAHSVEADQAVQVAPDDDDNVAADKRAMEQAQGLTPAARAY
GINEGAHRDLIPGL