Protein Info for Ga0059261_2712 in Sphingomonas koreensis DSMZ 15582

Annotation: Isopenicillin N synthase and related dioxygenases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 PF14226: DIOX_N" amino acids 9 to 125 (117 residues), 92.9 bits, see alignment E=2.3e-30 PF03171: 2OG-FeII_Oxy" amino acids 171 to 274 (104 residues), 82.2 bits, see alignment E=2.9e-27

Best Hits

KEGG orthology group: K06892, (no description) (inferred from 66% identity to sjp:SJA_C1-14850)

Predicted SEED Role

"Oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WEN9 at UniProt or InterPro

Protein Sequence (316 amino acids)

>Ga0059261_2712 Isopenicillin N synthase and related dioxygenases (Sphingomonas koreensis DSMZ 15582)
MSDTLLAEVPLVSLADQKSDPDGFAAALGGSFERFGFAMVSDHGVPQDLIDRAWAATKAF
FDLPEEEKRGYFVAGGGGARGYTPFKTEIAKGAEYVDLKEFWHIGRELPAGHRFETNMAP
NIWPDRPEGFRDTFLELFAAFDTAGDKLLSAIARHLGLEPDWFDPAVKDGNSVLRLLHYP
PVTEDAPNVRAGAHEDINLITLLLGAEEAGLELLDKDGQWLPVKPPEGAMVVNVGDMLQR
LTNHVLPSTTHRVVNPPVERRGTPRYSMPFFLHPAPDFLIKALPQCVTAENPEREPPITA
HDYLAERLREIGLTKK