Protein Info for Ga0059261_2039 in Sphingomonas koreensis DSMZ 15582

Annotation: phenylalanyl-tRNA synthetase, alpha subunit (EC 6.1.1.20)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 PF02912: Phe_tRNA-synt_N" amino acids 23 to 88 (66 residues), 73.7 bits, see alignment E=9.2e-25 TIGR00468: phenylalanine--tRNA ligase, alpha subunit" amino acids 41 to 348 (308 residues), 320.5 bits, see alignment E=6.3e-100 PF01409: tRNA-synt_2d" amino acids 93 to 348 (256 residues), 320.6 bits, see alignment E=7.1e-100

Best Hits

Swiss-Prot: 78% identical to SYFA_NOVAD: Phenylalanine--tRNA ligase alpha subunit (pheS) from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)

KEGG orthology group: K01889, phenylalanyl-tRNA synthetase alpha chain [EC: 6.1.1.20] (inferred from 79% identity to sjp:SJA_C1-34560)

Predicted SEED Role

"Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20)" (EC 6.1.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.1.1.20

Use Curated BLAST to search for 6.1.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6JFS0 at UniProt or InterPro

Protein Sequence (365 amino acids)

>Ga0059261_2039 phenylalanyl-tRNA synthetase, alpha subunit (EC 6.1.1.20) (Sphingomonas koreensis DSMZ 15582)
MTTDLDQLRAELLASIDASSGVDALDAVRVHALGKQGAVTGLLKTLGGMSPEERQETGPR
IHALREAVTDAIAARKAALEGAALEAKLAAETLDMTLPADSVPAGSVHPVSQVMDELAEI
FADLGFAVATGPEIEDDWHNFTALNIPETHPARAMHDTFYLAGDHASPMVLRTHTSPVQI
RAMKAAGGHKPVRIIAPGRTYRSDSDATHTPMFHQVEGLVIDKGITLGHLKWTLETFLKA
FFERDDIVLRLRPSYFPFTEPSAEVDVGYTLINGKRVIGGDPSKGDGGWMEVLGSGMVHR
KVIAAGGYDPDEWQGFAFGCGIDRLAMLKYGMDDLRAFFDGDLRWLKHYGFSALDVPTLS
GGVGA