Protein Info for Ga0059261_1698 in Sphingomonas koreensis DSMZ 15582

Annotation: Beta-lactamase class C and other penicillin binding proteins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 659 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 522 to 543 (22 residues), see Phobius details amino acids 564 to 583 (20 residues), see Phobius details amino acids 594 to 617 (24 residues), see Phobius details amino acids 629 to 654 (26 residues), see Phobius details PF00144: Beta-lactamase" amino acids 71 to 378 (308 residues), 191.7 bits, see alignment E=9.8e-61

Best Hits

KEGG orthology group: None (inferred from 48% identity to swi:Swit_4612)

Predicted SEED Role

"Beta-lactamase (EC 3.5.2.6)" in subsystem Beta-lactamase or Tn552 (EC 3.5.2.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.6

Use Curated BLAST to search for 3.5.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WBX0 at UniProt or InterPro

Protein Sequence (659 amino acids)

>Ga0059261_1698 Beta-lactamase class C and other penicillin binding proteins (Sphingomonas koreensis DSMZ 15582)
MRSIVQKALLPFALLLGVGASGQAQTPAPAAPKPAQLAPAAAPAAAPLAPGARPLTKEDV
DGWLDGLMPYALARGDLAGAVIVVVKDGQVLTQRGFGYADVAKRSPVDPDRTLFRPGSVS
KLFTWTAVMQEVEAGRIDLDKDVNAYLDFKIPAYLGKPVTMRQLMTHTAGFEEHGKRTIF
EDIKFNISLGDYVKVQPKRIYAAGTTPAYSNYGTALAGYIVERTSKMSFDDYVEQRIFRP
LGMAQSTFRQPLPKGFEAHMAAGYRKGSDAASKFEIVGPAPAGSLSSTGADMAKFMIAHL
NQGAGLMKPETAKTMHDTPLTMLPPLNRMELGFFETNINGRQVIAHLGDTQLFHTALHLF
MNEKIGLYLSLNATGAEGAAGPVRKALFEKFADRYLPGNEMPATRVDAKTSAEHARMMAG
NWLNSRRAESNFYALASLVGQFTVSVGPNGELAVPALRDINNAPTKWVETAPFVWHNANG
HGRLAAQVVDGKVVRWSMDGLSPFMVFDRAPVSKSAAWIKPAFYAGFAVLLLTFLQWPVS
ALIRRSYKAPLTLSRRSLLAYRGVRVASGLVIALTTAWLVSLTTLKAIPSFDPWLWFLQI
AGLIIFVGGVLIALWNLRIVRQEKRGWFRTIWAVLVLLAMMLALHIAWTFGLIAMTVNY