Protein Info for Ga0059261_1581 in Sphingomonas koreensis DSMZ 15582

Updated annotation (from data): Maltose or maltodextrin glucosidase (EC 3.2.1.20)
Rationale: Specifically important for: D-Maltose monohydrate; a-Cyclodextrin. The first step in catabolism of maltose or longer maltodextrin polymers. The phenotype on maltose implies that maltose is also a substrate, which was ambiguous with the original SEED annotation (SEED_correct)
Original annotation: Glycosidases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00128: Alpha-amylase" amino acids 76 to 454 (379 residues), 206.3 bits, see alignment E=5e-65

Best Hits

KEGG orthology group: None (inferred from 66% identity to sal:Sala_0183)

Predicted SEED Role

"Maltodextrin glucosidase (EC 3.2.1.20)" in subsystem Maltose and Maltodextrin Utilization (EC 3.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.20

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WBL5 at UniProt or InterPro

Protein Sequence (604 amino acids)

>Ga0059261_1581 Maltose or maltodextrin glucosidase (EC 3.2.1.20) (Sphingomonas koreensis DSMZ 15582)
MRSLAFALTLLAGTVASAQTAAPAELRARAAETEVLYFLLPDRFENGDPSNDRGGLRGDR
LTTGFDPAHKGFFHGGDLKGLIRRLDYIQSLGASAIWLGPIYKNKPVQGGPGQETAGYHG
YWITDFTRVDPHFGTNDEMKAFVDAAHARGIKVYLDIITNHTADVIQYRECPKSACDYRS
RADYPYQRKGGVKGAAINPGFAGDGVQTPENFAKLSDPNYAYTTVVPEAERTVKVPAWLN
DPIHYHNRGNTTFRNESSTMGDFVGLDDLMTESPRVLQGFIDIYGAWIDQFGIDGFRIDT
ARHVNPEFWQGFSKAMIERAKARGIPNFHIFGEVANEGDVGDLALHTRVHQLPSVLDFGF
RAAVQHTVAGEKGPDMLAAMFDRDALYEGGAEAALRLPTFISNHDHGRFSTDVRKAFPKA
SDDEVLARVKLAHAMLLLLRGVPTIYSGDEQGFVSDGNDQDAREDMFPSKVAIYNDNRLL
GTDKTTADSNFDTGHPLYMEISKLSAIRKATPALSRGRQVTRAYDEKPGLFAVSRFDPAS
GAEVLVAFNTSAAPITRQVEVGVSSTAFAPLVGQCAASASAPGSVTVTLPAFGYVACVAA
GGAK