Protein Info for Ga0059261_1052 in Sphingomonas koreensis DSMZ 15582

Annotation: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF11969: DcpS_C
  • amino acids 13 to 117 (105 residues), 48.4 bits, E=1.3e-16
• PF01230: HIT
  • amino acids 20 to 117 (98 residues), 88.9 bits, E=2.8e-29

Best Hits

Swiss-Prot: 70% identical to YHIT_AZOBR: Uncharacterized 13.2 kDa HIT-like protein in hisE 3'region from Azospirillum brasilense

KEGG orthology group: None (inferred from 78% identity to sal:Sala_2381)

Predicted SEED Role

"Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17)" (EC 3.6.1.17)

KEGG Metabolic Maps

• Purine metabolism
• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.17

Sequence Analysis Tools

See A0A1L6J9P2 at UniProt or InterPro

Protein Sequence (125 amino acids)

>Ga0059261_1052 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases (Sphingomonas koreensis DSMZ 15582)
MPIDATQPYDDQNIFAKILRGEIPSKRVYEDAYAIAFHDINPLAPTHLLVIPTGAYVSWD
DFSARASDAEIAGFVRAVGIVARQAGAVEPGYRLLANVGANGGQEVPHLHIHIFAGKTLG
PMLTR