Protein Info for Ga0059261_0847 in Sphingomonas koreensis DSMZ 15582

Annotation: Acyl-CoA dehydrogenases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 PF02771: Acyl-CoA_dh_N" amino acids 6 to 139 (134 residues), 42.8 bits, see alignment E=1.3e-14 PF02770: Acyl-CoA_dh_M" amino acids 143 to 244 (102 residues), 74.1 bits, see alignment E=1.7e-24 PF00441: Acyl-CoA_dh_1" amino acids 256 to 405 (150 residues), 124.3 bits, see alignment E=9.8e-40 PF08028: Acyl-CoA_dh_2" amino acids 273 to 381 (109 residues), 46.5 bits, see alignment E=9.3e-16

Best Hits

KEGG orthology group: K00249, acyl-CoA dehydrogenase [EC: 1.3.99.3] (inferred from 73% identity to sjp:SJA_C1-18600)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7, 1.3.99.3

Use Curated BLAST to search for 1.3.8.7 or 1.3.99.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6JA89 at UniProt or InterPro

Protein Sequence (427 amino acids)

>Ga0059261_0847 Acyl-CoA dehydrogenases (Sphingomonas koreensis DSMZ 15582)
MDFTLTERETYFRDRVKGFIDQHVMPRNGDYYRQAAEGERWKVLPVIEELKEVARAQGLW
NFFMPPHSGQTHVDDSFEFEGTQLTNLEYALCAEEMGRAGWASEVFNCSAPDTGNMEVLH
RYGTRAHKDRWLRPLMNGEIRSAFLMTEPDVASSDATNIQTSMVRDGDHYVINGRKWWSS
GVGDPRCAVAIVMGKTNPDASRHAQQSQILVPMDTPGVRVERMLSVFGYDHAPHGHGEVV
LENVRVPVDNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAEAALELMCKRLLSRVAFGK
RIADHSIWEQRVAEARSNLEMMRLLCLKAADMMDKAGNKSAQGEIAMIKAMGPRMTLQIL
DDAIQAFGGAGVSGDTPLASAWASMRTLRFADGPDEVHNRAIARAEFGKYGDFKADRVSS
GDMAVSR