Protein Info for Ga0059261_0820 in Sphingomonas koreensis DSMZ 15582

Annotation: Holliday junction DNA helicase subunit RuvA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 199 PF01330: RuvA_N" amino acids 1 to 61 (61 residues), 63.1 bits, see alignment E=4.3e-21 PF14520: HHH_5" amino acids 72 to 130 (59 residues), 55.1 bits, see alignment E=1.7e-18 PF07499: RuvA_C" amino acids 151 to 196 (46 residues), 37.1 bits, see alignment 7.2e-13

Best Hits

Swiss-Prot: 67% identical to RUVA_SPHWW: Holliday junction ATP-dependent DNA helicase RuvA (ruvA) from Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)

KEGG orthology group: K03550, holliday junction DNA helicase RuvA (inferred from 73% identity to sch:Sphch_2066)

Predicted SEED Role

"Holliday junction DNA helicase RuvA" in subsystem DNA-replication or RuvABC plus a hypothetical

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8W9J5 at UniProt or InterPro

Protein Sequence (199 amino acids)

>Ga0059261_0820 Holliday junction DNA helicase subunit RuvA (Sphingomonas koreensis DSMZ 15582)
MIAHLNGHLAATGIDHAVIDVNGVGYLVGASAKTLAALGSLGEFVTVHTEMLVSEDSIRL
MGFASADERNWFRLLTSVQGVGAKVALAILSILSPAEVQTAVARADAAMIARANGVGPKL
AQRIVNELKDKAGGIALGGGGVGAAIPAGGAANDAVSAMLNLGFRPAEASNAVNAAMDEL
GGGASLDALVRLALRKAAK