Protein Info for Ga0059261_0674 in Sphingomonas koreensis DSMZ 15582

Annotation: excinuclease ABC, A subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 1000 TIGR00630: excinuclease ABC subunit A" amino acids 5 to 972 (968 residues), 1434.5 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 131 to 238 (108 residues), 138.1 bits, see alignment E=2.5e-44 PF17755: UvrA_DNA-bind" amino acids 336 to 447 (112 residues), 124.1 bits, see alignment E=7.8e-40 PF00005: ABC_tran" amino acids 861 to 909 (49 residues), 25.5 bits, see alignment 4.6e-09

Best Hits

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6JAK9 at UniProt or InterPro

Protein Sequence (1000 amino acids)

>Ga0059261_0674 excinuclease ABC, A subunit (Sphingomonas koreensis DSMZ 15582)
MLTHISVRGAREHNLKGVDIDIPRDTLTVITGLSGSGKSSLAFDTIYAEGQRRYVESLSA
YARQFLEMMQKPNVEHIEGLSPAISIEQKTTSRNPRSTVATVTEIYDYMRLLWARVGVPY
SPATGLPIAAQTVSQMVDRVLALPEGTRLLLLAPVVRGRKGEYRKELAEWQKAGFQRVRI
DGETYLIEDAPALDKKYKHDIEVVVDRLVVRDDIATRLAESFETALKLADGLAYIDLVDT
TVEALSSPLPLAGGAGGGRVNEAPQTFKAEPSATNVTGGSMKGTGIPDNRIVFSEKFACP
VSGFTIPEIEPRLFSFNAPQGACPACDGLGERLVFDEDLVVPNHDLSIKKGAVVPWAKSN
PPSPYYMQVLGSLAREFGFSLDTPWKDLPGEVQLIILHGTGGKPVTLTFVDGKKSYDVKK
PFEGVIGNLNRRMLQTESAWMREELSKYQASHACETCDGARLKPEALAVKIAGRDISSVT
RLSVTDALPFFANLPADLTPQQREIAKAILKEIDERLGFLNNVGLDYLNLNRTSGTLSGG
ESQRIRLASQIGSGLSGVLYVLDEPSIGLHQRDNDMLLATLRRLRDLGNTVLVVEHDEDA
IRTADYVIDMGPGAGVHGGQIVAHGSFEQVLATEGSITADYLNGTRRIDVPAKRRKGTGK
KLTVHNATANNLTGVTASIPLGTFTCITGVSGSGKSSFTIDTLYAAAARQLNGARLLAGK
HDKVTGLEHLDKVIDIDQSPIGRTPRSNPATYTGAFTAIRDWFAGLPEAQARGYKPGRFS
FNVKGGRCEACTGDGLLKIEMHFLPDVYVTCDVCHGQRYNRETLEVKFKGMSIADVLDMT
VEDAVEFFKAVPPIRDKMAMLAEVGLGYIKVGQQATTLSGGEAQRVKLAKELARRATGQT
LYILDEPTTGLHFEDVRKLLEVLHALVEQGNTVVVIEHNLDVIKTADWILDLGPEGGVKG
GEIVAEGTPETVVKAPRSYTGKYLAPLLERGRVGESVAAE