Protein Info for Psest_1028 in Pseudomonas stutzeri RCH2

Annotation: Cyclic nucleotide-binding domain.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 PF00027: cNMP_binding" amino acids 152 to 234 (83 residues), 71.9 bits, see alignment E=1.8e-24

Best Hits

KEGG orthology group: None (inferred from 95% identity to psa:PST_3266)

Predicted SEED Role

"cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GJM4 at UniProt or InterPro

Protein Sequence (265 amino acids)

>Psest_1028 Cyclic nucleotide-binding domain. (Pseudomonas stutzeri RCH2)
MYLLGEQPAYADRLINRLQTIPSQLLEGLQPSGPNLELKHTDDLCAELPAQQLFIIETGL
LHAQIDGKALFYLQEGDLVGLRQAGDLPECRYCTDEPISLIPYSRNAAFQHIHADAHRQE
LFTQYLIGHTALLGDALARLKQPEIRPSTGFKHFAVGEELIRQGDEADNVFIIIEGHADA
IVDGQKVGDVQKDEIFGAMAVFTRERRSATVVASEPCTVMVIPKEQFLGLTQSNPRIAHS
LIESMARRIDLLNKEVTHLRVNVAV