Protein Info for PGA1_c10020 in Phaeobacter inhibens DSM 17395

Annotation: Putative protein-S-isoprenylcysteine methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 153 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 38 to 59 (22 residues), see Phobius details amino acids 95 to 121 (27 residues), see Phobius details PF04191: PEMT" amino acids 43 to 139 (97 residues), 43.8 bits, see alignment E=1.5e-15

Best Hits

KEGG orthology group: None (inferred from 60% identity to sil:SPO2821)

Predicted SEED Role

"Putative protein-S-isoprenylcysteine methyltransferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EXW7 at UniProt or InterPro

Protein Sequence (153 amino acids)

>PGA1_c10020 Putative protein-S-isoprenylcysteine methyltransferase (Phaeobacter inhibens DSM 17395)
MKWIDVPPVWLLGFAVLAWCQAQFLPLGLGFSTGPIAAIIDLLSGLLIGAGIVLMLLAVA
EMRRQKTTLHPHGDPSQLVQSGIFKRSRNPIYLGDCLLLLGLVLRFDAVLSLALLPIFVW
VLERRFILPEENRLRRQFRADWARYEQKTRRWL