Protein Info for PGA1_c09790 in Phaeobacter inhibens DSM 17395

Annotation: cold-shock DEAD box protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 713 PF00270: DEAD" amino acids 32 to 201 (170 residues), 138.3 bits, see alignment E=3.3e-44 PF00271: Helicase_C" amino acids 241 to 347 (107 residues), 95.6 bits, see alignment E=3.3e-31 PF03880: DbpA" amino acids 463 to 522 (60 residues), 53.7 bits, see alignment 2.6e-18

Best Hits

KEGG orthology group: K05592, ATP-dependent RNA helicase DeaD [EC: 3.6.4.13] (inferred from 61% identity to sit:TM1040_0590)

Predicted SEED Role

"FIG003033: Helicase domain protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EKG4 at UniProt or InterPro

Protein Sequence (713 amino acids)

>PGA1_c09790 cold-shock DEAD box protein A (Phaeobacter inhibens DSM 17395)
MPSGGAPRSKRNEILKTALEQALQARGYEHLTPVQEAVTAAELDQSDLLVSAQTGSGKTV
GFGLAMAPTLLGDAEKLDRADLPLALVIAPTRELALQVKRELGWLYAEAGAHVVSTVGGM
DMRDERRALERGAHIVVATPGRLRDHIMRGSINLSQVRAVVLDEADEMLDLGFREDLEFI
LGESPEDRRTLMFSATVPTGIARLAETYLKDHQRIKTVAEASQHADIEYQMLAVAQRDVE
NAVINVLRFHESPNAIVFCNTRAVVNRMTTRLSNRGFSVVALSGELSQAERSNALQSLRD
GRARVCVATDVAARGIDLPKLDLVIHADLPSSHETLLHRSGRTGRAGRQGVSALIVPPKA
KGKALRLLRSAKITAETSPAPSADDVRTRDFERLLGDKAWSEPVSENETAPVAELVERFS
PEQLAVAYLRLFHDRHSAPEELSDPQHDKREREERAPFGPSVWFAVSGGRKAGAEPRRLL
PALCNAGGLTKDDIGAIRVQFDQSYVEVRESSAESFWGAVKHDGLEEGANVTRLDKAPDL
PKSPRPQGRDGGGFRDDKRGHRGQDRGDRGGERGERKPYGDKPRSDKPSYGDKPRGEKSY
GDKPRASKPYGDKPRGDKPAYGDKPRFDKPKRTGEGGKATVTARGSSDRGATPSAPAKPA
VPGKPKGDWSNPGKSGRKGPPPPKGKPNSKKNKARAVVSGKPGGSARPQRKGS