Protein Info for PGA1_c09760 in Phaeobacter inhibens DSM 17395

Annotation: putative aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 PF01321: Creatinase_N" amino acids 17 to 152 (136 residues), 59.9 bits, see alignment E=7.4e-20 PF16189: Creatinase_N_2" amino acids 156 to 313 (158 residues), 128.4 bits, see alignment E=5.6e-41 PF00557: Peptidase_M24" amino acids 319 to 527 (209 residues), 165.3 bits, see alignment E=3.5e-52 PF16188: Peptidase_M24_C" amino acids 541 to 600 (60 residues), 65.2 bits, see alignment 8.2e-22

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 72% identity to sit:TM1040_0641)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.9

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EXU2 at UniProt or InterPro

Protein Sequence (600 amino acids)

>PGA1_c09760 putative aminopeptidase (Phaeobacter inhibens DSM 17395)
MFQTFDVATRPDQGPPRLNALRAEMQQEALNGFLVPRADAHQGEYVAPGDERLAWLTGFT
GSAGFCAVLRDIAGVFIDGRYRTQVKQQVAEVYTPVHWPEVQLADWLKEQLPEGGRIGYD
PWLHSASQIKTLTASLDHHGFDFVQCDNLVDRIWPDQPAPPMQPVIAHPVEYAGTTAVAK
IASLAEGMRNAGQSAAVITLPDSIMWLLNIRGSDIAHNPVAHGFAILHADARVDLFMNKD
KLADVAAHLGPDVTVQAPENFLPAVADLSQAYNAAVAADLTTLPQIVADQLGEALVAAGD
PCALPKARKCATEIEGSAAAHLRDGAAVVETLAWLDAQPPGTVTEIDVVKHLEATRRKDP
KLRDISFETISGTGPNGAIIHYRVSDDSNATLEEGHLLVLDSGGQYLDGTTDITRTLAIG
TPPQEAREAYTRVLQGMIAMSRLRWPKGLAGRDIEAVGRMPLWLAGQDFNHGLGHGVGAF
LSVHEGPQRLSRAGTVPLDPGMILSNEPGYYREGAFGIRIENLLVVEPAPELDSADADRD
MLSWRTLTYAPLDWRLIVADILTTAERDWLNTYHAAVADKIGPNVTAEARRWLDAATAPL