Protein Info for Psest_0974 in Pseudomonas stutzeri RCH2

Annotation: phosphoglucosamine mutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02878: PGM_PMM_I
  • amino acids 3 to 134 (132 residues), 153.3 bits, E=6.6e-49
• TIGR01455: phosphoglucosamine mutase
  • amino acids 6 to 441 (436 residues), 628.8 bits, E=2.2e-193
• PF02879: PGM_PMM_II
  • amino acids 156 to 253 (98 residues), 69.7 bits, E=5.6e-23
• PF02880: PGM_PMM_III
  • amino acids 257 to 360 (104 residues), 111.1 bits, E=6.7e-36
• PF00408: PGM_PMM_IV
  • amino acids 372 to 438 (67 residues), 56.8 bits, E=3.7e-19

Best Hits

Swiss-Prot: 97% identical to GLMM_PSEU5: Phosphoglucosamine mutase (glmM) from Pseudomonas stutzeri (strain A1501)

KEGG orthology group: K03431, phosphoglucosamine mutase [EC: 5.4.2.10] (inferred from 97% identity to psa:PST_3317)

MetaCyc: 65% identical to phosphoglucosamine mutase (Escherichia coli K-12 substr. MG1655)
Phosphoglucosamine mutase. [EC: 5.4.2.10]

Predicted SEED Role

"Phosphoglucosamine mutase (EC 5.4.2.10)" in subsystem Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 5.4.2.10)

MetaCyc Pathways

• O-antigen building blocks biosynthesis (E. coli) (11/11 steps found)
• colanic acid building blocks biosynthesis (10/11 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis I (5/5 steps found)
• dTDP-β-L-rhamnose biosynthesis (5/5 steps found)
• superpathway of anaerobic sucrose degradation (15/19 steps found)
• glycogen degradation I (7/8 steps found)
• UDP-α-D-glucose biosynthesis (2/2 steps found)
• sucrose biosynthesis I (from photosynthesis) (7/9 steps found)
• glucose and glucose-1-phosphate degradation (4/5 steps found)
• sucrose biosynthesis II (6/8 steps found)
• glycogen biosynthesis I (from ADP-D-Glucose) (3/4 steps found)
• starch degradation V (3/4 steps found)
• GDP-α-D-glucose biosynthesis (2/3 steps found)
• trehalose degradation V (2/3 steps found)
• glycogen degradation II (4/6 steps found)
• superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis (4/6 steps found)
• chitin biosynthesis (6/9 steps found)
• sucrose degradation II (sucrose synthase) (3/5 steps found)
• starch degradation III (2/4 steps found)
• sucrose degradation IV (sucrose phosphorylase) (2/4 steps found)
• peptidoglycan recycling I (9/14 steps found)
• D-galactose degradation I (Leloir pathway) (2/5 steps found)
• glucosylglycerol biosynthesis (2/5 steps found)
• glycogen biosynthesis III (from α-maltose 1-phosphate) (4/8 steps found)
• starch biosynthesis (5/10 steps found)
• CDP-6-deoxy-D-gulose biosynthesis (1/5 steps found)
• CMP-legionaminate biosynthesis I (2/10 steps found)
• superpathway of dTDP-glucose-derived O-antigen building blocks biosynthesis (7/19 steps found)
• superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (9/24 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (14/33 steps found)
• streptomycin biosynthesis (1/18 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.10

Sequence Analysis Tools

See L0GIE9 at UniProt or InterPro

Protein Sequence (445 amino acids)

>Psest_0974 phosphoglucosamine mutase (Pseudomonas stutzeri RCH2)
MTRKYFGTDGIRGHVGQAPITPDFMLKLGWAAGMAFRKQGKCRILIGKDTRISGYMFESA
LQAGLSAAGADVLLLGPMPTPAVAYLTRTFHAEAGIVISASHNPHHDNGIKFFSGRGTKL
PDEVELMIEELIDAPMTVVESAQLGKASRINDAAGRYIEFCKSSVPTSTDFSGLKLVIDC
AHGATYKVAPSVFRELGAEVVVIGAQPDGLNINADVGSTHVGQLQKAVVDHGADLGIAFD
GDGDRVMMVDHTGAVVDGDELLYIIATDLQERDRLSGGVVGTLMSNLGLELALKARDIPF
TRAKVGDRYVIAEMLDRSWVLGGENSGHIVCAQHTTTGDAIIAALQVVLALRRRGQTLAQ
ERLAWHKCPQVLINVRFSGDRDPISHPSVQAACDSVTERMAGRGRVLLRKSGTEPLVRVM
VEGDDETQVRGMAEELAKIVTEVCA