Protein Info for HP15_807 in Marinobacter adhaerens HP15

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 661 PF08668: HDOD" amino acids 9 to 152 (144 residues), 124.4 bits, see alignment E=6.3e-40 PF01590: GAF" amino acids 286 to 413 (128 residues), 23.7 bits, see alignment E=8.9e-09 PF02518: HATPase_c" amino acids 544 to 653 (110 residues), 75.2 bits, see alignment E=8.6e-25

Best Hits

Predicted SEED Role

"Nitrogen regulation protein NtrB (EC 2.7.13.3)" (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PR36 at UniProt or InterPro

Protein Sequence (661 amino acids)

>HP15_807 histidine kinase (Marinobacter adhaerens HP15)
MHIAPDLQLPSLPEVTLRALDACHQDESYRKISEIVSADTALVARILALANSALYGPSTP
IRSVDQALLRLGTRRFHTLVLTAALRQLLFELGGDEWQQLRDFWRHSLTTALTARALATL
TRYPEPDEAFMLGMLHNIGELIAIKTPATEAKQHYLDHQSDIAAELVASWGLGPMASDAM
RYQQALPSELRDAGHLVKLISLATRLALSDAAGIAAAGTVFGLNEELTREINRRIGHEVS
GMAASLGIPLDENYCGESASRQLKQTILRQAMANQAINLADLTGETEDILAETVNSLTLI
TGLPALCFGHTGENLVLLSGTIGDIPDLAVTAKPGGSVLTEAFISGLPVSLGDRSPTVLD
RQLLSLLHTPSILAVPVNNGGDCPGVFALGTDNEHLPTTLELADIFTAQLASVLADRVPA
QTGAEASTESLDQEIARDRLRKQVHEVSNPLTIIRQYIYQLRGRLEDAGVQQELDVIRDE
LDRAGNLLLQMSHTDTVDQGDDGVELNAELESLARILEDSLFSSDSRSLRLSLCSEPTRV
AAGPTRIRQIVINLVRNAAESLADDGGTVEIRTSSPVWQNHRTWVELEISDTGRGIPGEV
RDALFSPVKTTKGEGHSGLGLSIVKQLVDDMEGIIACRTGQEGTTFRILLPAASHKKNET
D