Protein Info for Psest_0800 in Pseudomonas stutzeri RCH2

Annotation: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00106: adh_short" amino acids 9 to 189 (181 residues), 119.1 bits, see alignment E=3.6e-38 PF08659: KR" amino acids 11 to 160 (150 residues), 27.9 bits, see alignment E=4.2e-10 PF01370: Epimerase" amino acids 11 to 135 (125 residues), 26.8 bits, see alignment E=6.7e-10 PF13561: adh_short_C2" amino acids 14 to 245 (232 residues), 129.2 bits, see alignment E=4e-41

Best Hits

KEGG orthology group: None (inferred from 93% identity to psa:PST_3543)

Predicted SEED Role

"short-chain dehydrogenase/reductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GF67 at UniProt or InterPro

Protein Sequence (247 amino acids)

>Psest_0800 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) (Pseudomonas stutzeri RCH2)
MKSEFQDRLAVVTGASSGIGLALCSALLQRGARVLAMSRSIGGLEPLLETHAEQLQWLRG
DVTSAEDLAQLARRAAQLGPVHYLVPNAGIAELADGLDMAAFDRQWAVNGAGALNTFAAL
RNELAKPASVVFVGTFLIRSTFPGLAAYIASKAALAAQARTLAVEFAPLDVRINMVSPGP
TATAIWGSLGLSDDQLESVAEGVTKRLLPGHFLESAAVANVILFQLSQGARGVFGQDWVV
DNGYTIS