Protein Info for PGA1_c08000 in Phaeobacter inhibens DSM 17395

Annotation: DNA polymerase III, gamma/tau subunits

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13177: DNA_pol3_delta2
  • amino acids 28 to 206 (179 residues), 124.7 bits, E=3.8e-40

Best Hits

KEGG orthology group: K02341, DNA polymerase III subunit delta' [EC: 2.7.7.7] (inferred from 75% identity to sit:TM1040_3592)

Predicted SEED Role

"DNA polymerase III delta prime subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

• Purine metabolism
• Pyrimidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

See I7EK01 at UniProt or InterPro

Protein Sequence (373 amino acids)

>PGA1_c08000 DNA polymerase III, gamma/tau subunits (Phaeobacter inhibens DSM 17395)
MSKDDAPLRADQTAGAPHPRETLHLFGQAQAEQDFLTAFNSDRLHHGWLLTGPQGVGKAT
LAWRIAAFLLSQPPAEDAGLFGAPPPATSLDIGMDHPVMHRIQALAEPGLASITRSVNDK
GKLRDQIVVDDIRALNKFFGLSATDGGRRVVIVDAADEMNTSAANALLKMLEEPPARTTL
LLVSHQPSRLLPTIRSRCRLLRFAPLSPEDMQAALTQAGAELPRQAEHLAALANGSVGAA
LRLLNLGGLQAYSDVVRLLDSMPRLDRQRAMTLAEQAAARGGADKFELLLTLIDTALARL
ARTGATGMAPQPEAAPQEAAVLSRLSPTPQKARAWADLAAQVTARMRHGQAVNLDPAALV
LDTVFKMQDTAAR