Protein Info for PGA1_c07930 in Phaeobacter inhibens DSM 17395

Annotation: two-component system response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 221 PF00072: Response_reg" amino acids 4 to 111 (108 residues), 84.1 bits, see alignment E=8.1e-28

Best Hits

Swiss-Prot: 43% identical to TCTD_SALTY: Transcriptional regulatory protein tctD (tctD) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K07774, two-component system, OmpR family, response regulator TctD (inferred from 77% identity to sil:SPO0187)

Predicted SEED Role

"Tricarboxylate transport transcriptional regulator TctD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DN31 at UniProt or InterPro

Protein Sequence (221 amino acids)

>PGA1_c07930 two-component system response regulator (Phaeobacter inhibens DSM 17395)
MRFLLVEDNLSLASAVEDRLRMDGHVVDHAPDLAVADDYAATADYDLILLDIMLPDGDGR
SFLKSHRSREGTTPVIVLTARSEVSDRVGVLDLGADDYITKPFDFSELEARCRAVLRRHG
GGSSNQKRFGALVFDPLAGTLVVGDKTVSLRNKELRLLEIFINAPDRIFSKSKLVDRLFS
YEEDVSENAIEVYVARLRKHLAGADVEITTVRGLGYRMSLA