Protein Info for Psest_0774 in Pseudomonas stutzeri RCH2

Updated annotation (from data): cytosine permease
Rationale: Specific phenotype: utilization of Cytosine
Original annotation: Purine-cytosine permease and related proteins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 54 to 77 (24 residues), see Phobius details amino acids 101 to 126 (26 residues), see Phobius details amino acids 132 to 151 (20 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 197 to 216 (20 residues), see Phobius details amino acids 228 to 253 (26 residues), see Phobius details amino acids 263 to 282 (20 residues), see Phobius details amino acids 307 to 325 (19 residues), see Phobius details amino acids 331 to 352 (22 residues), see Phobius details amino acids 373 to 406 (34 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 14 to 382 (369 residues), 81.2 bits, see alignment E=3.6e-27

Best Hits

KEGG orthology group: K10974, cytosine permease (inferred from 98% identity to psa:PST_3569)

Predicted SEED Role

"Cytosine permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GHV4 at UniProt or InterPro

Protein Sequence (425 amino acids)

>Psest_0774 cytosine permease (Pseudomonas stutzeri RCH2)
MKQPVDTDYPLSEVPAGARKGLWSTSILLFGFTFFTATMFAGGKIGLAFDFKTMLWAAVI
GNLLLGLYAAALGLIACRSGLNSVLMGRFCFGEAGSRLSDFLLGFTQIGWYAWGTATIAI
VLVRLLALPESWTMPLMVLFGFGFCLTAFVGYKGLDLLSRIAVPAMLILLIASLWTATRD
IGGLDGLLAVQPGDSLTLGMAITMIFGTFVSGATQATNWTRFARSSKVAVWASLIGFFIG
NGLMIVAGAYGAIVYQQPDIVEVLVLQGLSMAAVVMLFLNLWTTQDNTIYNFAAAGCNLL
RTERRRLVTLGGAFVGTLLALGGMYELLIPFLILLGSIIPPIGGVIMADYFYRHRGHYPK
LAEARLPKYNSLGLAAYVLGAACAYFSPWVAPIVGILVAAAAYIVLYEGQRLALSRTVLT
QTDAR