Protein Info for PGA1_c00780 in Phaeobacter inhibens DSM 17395

Annotation: putative chromosome segregation protein SMC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1151 PF02463: SMC_N" amino acids 4 to 1136 (1133 residues), 194 bits, see alignment E=3.8e-61 PF13476: AAA_23" amino acids 5 to 204 (200 residues), 56.8 bits, see alignment E=7.6e-19 PF13304: AAA_21" amino acids 26 to 69 (44 residues), 27.2 bits, see alignment (E = 6e-10)

Best Hits

Swiss-Prot: 69% identical to SMC_RHOS1: Chromosome partition protein Smc (smc) from Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)

KEGG orthology group: K03529, chromosome segregation protein (inferred from 80% identity to sit:TM1040_2587)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DWL4 at UniProt or InterPro

Protein Sequence (1151 amino acids)

>PGA1_c00780 putative chromosome segregation protein SMC (Phaeobacter inhibens DSM 17395)
MRFSKLRLNGFKSFVDPTDLLIADGLTGVVGPNGCGKSNLLEALRWVMGENRPKAMRGGG
MEDVIFAGTSSRPARNFAEVSLQIDNSERLAPSGFNESDNLEILRRITRDVGSAYKTNGK
DVRARDVQMLFADASTGAHSPALVRQGQIAELINAKPKARRRILEEAAGISGLYQRRHEA
ELKLKNTEQNLLRVDDVIEQLAAQLSQLARQARHAQRYRDIGEQLRRAEGMLLYRRWREA
DDARLEAEDILRTRETQAAKAEALARVADGKRLEAESALPPLREEEAIAAAVLQRLFVQR
DALSDQEAQARQTIETLTNRVAQLGRDIERESGLNRDAGETIERLDWEQRELARAAIGHD
DRMAEAAERSREAGSVLQAREEHLTSLTEDVARLAARHQSAQRQVEDCRRGLLRAEEEGG
ASRDAMVEAGDTLAQAEAAFEAAIEAEEEARAAAELADEALAAADEARNDTQSREAEARA
RRSEAEGELGALRAEVTALAKLVERDTAEGGHVLDEMRVAAGYEKALGAALADDLRAPLA
EVDGPSGWVTLPPYDGDAPLPAGAVPLSLHVSSPDALHRRISQVGLVDADAARDLHSRLM
PGQRLVTLEGDLWRWDGFRAWAEDAPSAAALRLEQMNRLEVLKQDMEHVGARADGAKAAH
EVLMRKLAEVTTADQTARQARRVADQRVADAARALSRAESHRNLSEGKLETLSIAVARHD
EDAAAAQAHLTEAEAAVEGLEDLAEARAKVEDIKQAVEAARITMLTHRSTQDELRREGEA
RTARGQQVTKDLSGWRHRLESADRRIAELTERRAATEEELQEAHQVPAEIAETHEELNLA
IEEAEARKAVASDALIGAETVLRDAVQNERECARLASEAREARARSEARCDAAREAVGHA
EARIREEQQTVPDALLASLDATPEDMPNAEELEAEVNRHKRQRDALGAVNLRAEEDARTV
QDEHDQLVREKADLEEAVKTLRSGIASLNREGRERLLTAFEEVNASFTMLFTHLFGGGEA
NLVMVESDDPLDAGLEIMCQPPGKKLSTLSLLSGGEQTLTAMALIFAVFLSNPAPICVLD
EVDAPLDDANVTRFCDLLDEMCRQTDTRFLIITHHAVTMARMDRLFGVTMQEKGVSQLVS
VDLKKAEALVA