Protein Info for PGA1_c07700 in Phaeobacter inhibens DSM 17395

Annotation: putative sulfopyruvate decarboxylase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 184 transmembrane" amino acids 40 to 59 (20 residues), see Phobius details TIGR03846: sulfopyruvate decarboxylase, beta subunit" amino acids 3 to 182 (180 residues), 244.1 bits, see alignment E=4.7e-77 PF02775: TPP_enzyme_C" amino acids 41 to 155 (115 residues), 65.2 bits, see alignment E=3e-22

Best Hits

Swiss-Prot: 44% identical to COME_METMP: Sulfopyruvate decarboxylase subunit beta (comE) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K13039, sulfopyruvate decarboxylase subunit beta [EC: 4.1.1.79] (inferred from 76% identity to rde:RD1_3813)

MetaCyc: 64% identical to sulfopyruvate decarboxylase beta subunit (Roseovarius nubinhibens ISM)
Sulfopyruvate decarboxylase. [EC: 4.1.1.79]

Predicted SEED Role

"Sulfopyruvate decarboxylase - beta subunit (EC 4.1.1.79)" (EC 4.1.1.79)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.79

Use Curated BLAST to search for 4.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EJX4 at UniProt or InterPro

Protein Sequence (184 amino acids)

>PGA1_c07700 putative sulfopyruvate decarboxylase subunit beta (Phaeobacter inhibens DSM 17395)
MIRSEILREIAPILRNELVVCNIGIPSQELHAIDDQPSNFYMLGTMGLASSIGLGLALAQ
PKPVIVIDGDGSILTNLGTLPTIGNNAPGNYILMIIDNGSYGSTGDQPTYTSQRTDLAAM
ARAAGCGRVIEVQDKDTRSALEQTLASGEATVLVVKCDSGNAKMPVITMDPVVIRDRFMT
AVTS