Protein Info for PGA1_c07670 in Phaeobacter inhibens DSM 17395

Annotation: two component regulatory sytem

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 580 transmembrane" amino acids 30 to 58 (29 residues), see Phobius details amino acids 75 to 100 (26 residues), see Phobius details amino acids 106 to 124 (19 residues), see Phobius details amino acids 129 to 155 (27 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details PF00512: HisKA" amino acids 202 to 268 (67 residues), 60.6 bits, see alignment E=1.9e-20 PF02518: HATPase_c" amino acids 316 to 428 (113 residues), 90.1 bits, see alignment E=2e-29 PF00072: Response_reg" amino acids 456 to 568 (113 residues), 88.1 bits, see alignment E=6.6e-29

Best Hits

Predicted SEED Role

"sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EXA1 at UniProt or InterPro

Protein Sequence (580 amino acids)

>PGA1_c07670 two component regulatory sytem (Phaeobacter inhibens DSM 17395)
MRLFSLSPDLVNSVASQNKLVRSDLPSRFASITLVSLLSLYFLSLQTIAVVYAAYVLVEL
VGLRVYRRLSSGVTLGGMVLFAGSAFVGVCVFNSLSLLLFLHPEPFPKLMGAMLLIIALN
HSVVARSAWFYFGIITAVPIILTVGYMVCATLLRVASPGEMIIAAVILLLGAAYMVHAMW
VQHHLTARLREALSAAEAASRAKSRFLAAMSHEIRTPLNAICGMSELIEEENSGSDTLRE
QTQLLRKSSQALTGILDDVLDHAKIESGQFELNLATASPREEISSAVEMYRPRADEKGLA
LAVSLAQSVPDYAECDALRLRQVIGNLVSNAVKYTETGQVEVVADCEDIGGRMMLRVAVF
DTGRGMTPEQSAKLFTDFYRAKDKNAPNVPGTGLGLAIARHLARIMGGDITVQTGRDWGS
CFTFLCPITALGASEVEVLPQQTARAETGELGDLSILLVDDTTSNRLVVRAFLKNSGVRI
TDAENGAEALDALERQPFDLVLLDMKMPVMDGRETLTEMLRRGGRVGATPVVMLTANAAP
EEQELFLRLGAVSYLSKPVKKSVLLSEIRKITSVPAARSA