Protein Info for Psest_0758 in Pseudomonas stutzeri RCH2

Annotation: Lactoylglutathione lyase and related lyases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 129 PF00903: Glyoxalase" amino acids 5 to 124 (120 residues), 95 bits, see alignment E=8.7e-31 PF13468: Glyoxalase_3" amino acids 5 to 119 (115 residues), 30.5 bits, see alignment E=7.5e-11 PF13669: Glyoxalase_4" amino acids 6 to 113 (108 residues), 48.9 bits, see alignment E=1.5e-16 PF18029: Glyoxalase_6" amino acids 10 to 124 (115 residues), 25 bits, see alignment E=4.9e-09

Best Hits

Swiss-Prot: 61% identical to YWKD_BACSU: Uncharacterized protein YwkD (ywkD) from Bacillus subtilis (strain 168)

KEGG orthology group: K08234, glyoxylase I family protein (inferred from 93% identity to psa:PST_3589)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GH68 at UniProt or InterPro

Protein Sequence (129 amino acids)

>Psest_0758 Lactoylglutathione lyase and related lyases (Pseudomonas stutzeri RCH2)
MLLSLHHAAIICSDYAVSKRFYTETLGLRVIAEHYRETRQSYKLDLALPDGGQIELFSFP
DAPPRPSRPEAQGLRHLAFAVDDVGACKAELEAKGVAVEPIRVDEYTGRRFTFFADPDGL
PLELYQRAS