Protein Info for PGA1_c07110 in Phaeobacter inhibens DSM 17395

Annotation: putative sodium/alanine symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 514 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 34 to 51 (18 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 118 to 142 (25 residues), see Phobius details amino acids 189 to 207 (19 residues), see Phobius details amino acids 226 to 247 (22 residues), see Phobius details amino acids 257 to 277 (21 residues), see Phobius details amino acids 283 to 306 (24 residues), see Phobius details amino acids 347 to 368 (22 residues), see Phobius details amino acids 407 to 429 (23 residues), see Phobius details amino acids 447 to 469 (23 residues), see Phobius details amino acids 475 to 494 (20 residues), see Phobius details TIGR00835: amino acid carrier protein" amino acids 58 to 501 (444 residues), 397.4 bits, see alignment E=3.7e-123 PF01235: Na_Ala_symp" amino acids 96 to 510 (415 residues), 420.1 bits, see alignment E=5.8e-130

Best Hits

KEGG orthology group: K03310, alanine or glycine:cation symporter, AGCS family (inferred from 87% identity to sil:SPO2370)

Predicted SEED Role

"Sodium:alanine symporter family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DYB3 at UniProt or InterPro

Protein Sequence (514 amino acids)

>PGA1_c07110 putative sodium/alanine symporter (Phaeobacter inhibens DSM 17395)
MNTLSKAAALAVPGALGLSGPLMAQTIDEKVNELFASSTGWFVNFIFSPFPGTSFPWIVA
WLVIAATIFTIYFGLIQFRAFPHSISLVKGDYSDPNDAGEVSHFQALATALSGTVGLGNI
AGVAVAVGIGGPGATFWMILAGLMGMASKFTECTLGVKYRNEYPDGTVSGGPMYYMTKGF
AARGLPGGKFMAVLFSIFCILGAFGGGNMFQANQAHAQLTNVLGDYPGWITGVIFAGVVF
AVIIGGLKSIASVTEKVVPFMGVLYVLTALVIILLNFDKIGWAFGQIFDGAFTGLGVAGG
MVGALIQGFKRAAFSNEAGVGSAAIAHSAVRTKEPITEGFVSLLEPFIDTVVICTMTALV
IIITGQLVSDPETGLYVLNEAGSAIQTVDGNSGVALTSAAFSSSFGWFKYILAIAVILFA
FSTMISWSYYGLKAWTFLFGESKTTELVFKVIFCLFVIIGAAASLGPVIDFSDAAIFAMA
VVNIVALYFLMPIVKGELNSYLARLKSGEIKKYQ