Protein Info for PGA1_c00710 in Phaeobacter inhibens DSM 17395

Annotation: ATP synthase a chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 54 to 72 (19 residues), see Phobius details amino acids 81 to 98 (18 residues), see Phobius details amino acids 109 to 129 (21 residues), see Phobius details amino acids 139 to 161 (23 residues), see Phobius details amino acids 167 to 191 (25 residues), see Phobius details amino acids 210 to 259 (50 residues), see Phobius details TIGR01131: ATP synthase F0, A subunit" amino acids 52 to 262 (211 residues), 203.1 bits, see alignment E=2.8e-64 PF00119: ATP-synt_A" amino acids 56 to 260 (205 residues), 207.7 bits, see alignment E=1e-65

Best Hits

Swiss-Prot: 74% identical to ATP6_ROSDO: ATP synthase subunit a (atpB) from Roseobacter denitrificans (strain ATCC 33942 / OCh 114)

KEGG orthology group: K02108, F-type H+-transporting ATPase subunit a [EC: 3.6.3.14] (inferred from 83% identity to sit:TM1040_2594)

Predicted SEED Role

"ATP synthase F0 sector subunit a"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7ET42 at UniProt or InterPro

Protein Sequence (267 amino acids)

>PGA1_c00710 ATP synthase a chain (Phaeobacter inhibens DSM 17395)
MGKLIFGAAFLLVLASGLFFAPAIPGLQIHPTDQFLVKPLGGAAELNFYTPTNVTLWMGL
AIVAIFALMVLGSAKRAIVPSRIQSVAELAYGFIYKMVEDVTGKDGLKFFPYIMTLFMFI
LTANMLGLIPGSFTTTSHFAVTAVLAMLVFVTVTVTGFVLHGTKFLGLFWVGSAPLALRP
VLAIIELISYFVRPVSHCIRLAGNVMAGHAVLKVFAGFAGALGLFSFLPIFAITAVYALE
VLVAFIQAYVFTILTCVYLKDALHPSH