Protein Info for PGA1_c06510 in Phaeobacter inhibens DSM 17395

Annotation: pyruvate, phosphate dikinase PpdK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00391: PEP-utilizers
  • amino acids 403 to 485 (83 residues), 83.6 bits, E=5.9e-28
• PF02896: PEP-utilizers_C
  • amino acids 499 to 850 (352 residues), 244.7 bits, E=1.2e-76

Best Hits

KEGG orthology group: K01006, pyruvate,orthophosphate dikinase [EC: 2.7.9.1] (inferred from 84% identity to sit:TM1040_2309)

Predicted SEED Role

"Pyruvate,phosphate dikinase (EC 2.7.9.1)" in subsystem Glycolysis and Gluconeogenesis or Glycolysis and Gluconeogenesis, including Archaeal enzymes or Pyruvate metabolism I: anaplerotic reactions, PEP (EC 2.7.9.1)

MetaCyc Pathways

• nitrogen remobilization from senescing leaves (6/8 steps found)
• C4 photosynthetic carbon assimilation cycle, NADP-ME type (4/7 steps found)
• C4 photosynthetic carbon assimilation cycle, NAD-ME type (5/11 steps found)
• C4 photosynthetic carbon assimilation cycle, PEPCK type (7/14 steps found)

KEGG Metabolic Maps

• Carbon fixation in photosynthetic organisms
• Pyruvate metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.9.1

Sequence Analysis Tools

See I7DMP1 at UniProt or InterPro

Protein Sequence (866 amino acids)

>PGA1_c06510 pyruvate, phosphate dikinase PpdK (Phaeobacter inhibens DSM 17395)
MQKHDQDMGGPTRDETPDSVLITPVAPIANHTHGGRAKCLQRLVRLDLPVPRTVALSFRA
VHGIAQGEMPDMASIVEAFPADALLCVRPSSQDPDWGGPGAILNIGMNDARYVDLCDSLG
RDGAAALYLRFVQSYAVHVARLDPDVFDDVEDGGPDALSEVLHAYEAETDEPFPQDPAEQ
LAAVLRSMARAWEGTSARLLRQAKGAPADAGLGLVVQEMVPGFGQGECGSGVLQLVNTKT
GQPQITGRYLSQSQGRDALGAGAEALYLERDPRGPSLEDSAPEAFADLKSHARLMRQRLR
EEMQVEFVIVSGAVHILDGVRVTRSAQAAVRIAVALAEDGIIPREEAIMRVDAHILTELL
HRQVAPDATRDVIGRGIAASPGAATGRLVFTAAEAQASAARGEPCILVRRETSPEDVRGM
HAAVGVLTERGGITSHAAVIGRGLGLPCIVGASNLKFHSKRKQLIATDGRVFTRGDTITI
DGSSGEVLAGQPEMLEAAEDGAFQTLLTWADEVRDIGIRANADTPEDAETARKFNAQGIG
LCRTEHMFFDPGRLTVMREMIFAETSEGRAAVLARLLPMQREDFFALFRIMEGLPVCIRL
FDPPLHEFLPTSKSGQRELSEALGIPVSDVTRRVEEMEEYNPMLGLRGVRLGVTVPEIYD
MQARAIFEATLDASKEGDPVVPEIMIPLVSAKREVELVKARIDAVALAVKAERGEDFTYR
LGVMVETPRAALRAGEISPHTAFLSFGTNDLTQMTYGLSRDDAGRFMSAYVNQGVFPEDP
FHVLDTDGVGELLKLGVQRGRAENPDITLSICGEHGGNPESIAFCREAGFDYVSCSPFRV
PVARLAAAQLAISSQTGKSPLESLKS