Protein Info for PGA1_c06120 in Phaeobacter inhibens DSM 17395
Annotation: Flp pilus assembly protein, ATPase CpaE
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02282, pilus assembly protein CpaE (inferred from 76% identity to sit:TM1040_2348)Predicted SEED Role
"Type II/IV secretion system ATPase TadZ/CpaE, associated with Flp pilus assembly" in subsystem Widespread colonization island
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See I7EUG7 at UniProt or InterPro
Protein Sequence (410 amino acids)
>PGA1_c06120 Flp pilus assembly protein, ATPase CpaE (Phaeobacter inhibens DSM 17395) MSSGMPQTEVNAIVACTISRDVQNFDLLIEDMEAVMGESWGDLGFNEALAFFNQSEAEAL EFVALALDSGDEDNLPLMGTIITEAKTRNIKVILIAEDVTPAALHNLLRQGADEFIPYPL PEGELQAAIERLRLAEAERTAEPQHVLKTGSQRDGAVIVCHGLAGGSGSTTLAVNLAWEL AQLSTSETPRVCLLDFDLQYGSVATYLDLPRREVVMEMLSDTENLDEDVFGQALVTYEDK LQVLTAPVDMIPLEFITPEDIERVVTLARSHFDFVVIDMPHTLVQWSETILNMAHVYFSM VELDMRSAQNALRLKRALQSEDLPFEKLRFALNRAPKFTDLSGKSRVKRMAESLGISIDL QLPDGGKQVAQSSDHGNPLASSAAKNPLRKEILKLAQSLHDLGQSDAAAA