Protein Info for PGA1_c05490 in Phaeobacter inhibens DSM 17395
Annotation: ureidoglycolate hydrolase AllA
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 58% identical to ALLA_RHOCB: Ureidoglycolate lyase (allA) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
KEGG orthology group: K01483, ureidoglycolate hydrolase [EC: 3.5.3.19] (inferred from 72% identity to sil:SPO0873)Predicted SEED Role
"Ureidoglycolate hydrolase (EC 3.5.3.19)" in subsystem Allantoin Utilization (EC 3.5.3.19)
MetaCyc Pathways
- allantoin degradation to glyoxylate II (1/5 steps found)
- superpathway of allantoin degradation in plants (1/8 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.5.3.19
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See I7DMG5 at UniProt or InterPro
Protein Sequence (161 amino acids)
>PGA1_c05490 ureidoglycolate hydrolase AllA (Phaeobacter inhibens DSM 17395) MKTVEIRPISAEGFAPFGDLIDCTGAPDKIINQGLCGRYHDRAQLAFTTGRAGLSLFNAE PRALPMPLLMVERHPEGSQAFIPMSETGFLVIVAPDAGGAPGQPLAFETQPGQAINFHRG TWHGVLTPLTAPGLFAVVDRIGDGANLEEHWFDTPYQVIRP