Protein Info for Psest_0538 in Pseudomonas stutzeri RCH2

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 666 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 183 to 205 (23 residues), see Phobius details amino acids 212 to 237 (26 residues), see Phobius details amino acids 244 to 268 (25 residues), see Phobius details amino acids 280 to 298 (19 residues), see Phobius details amino acids 304 to 327 (24 residues), see Phobius details amino acids 335 to 356 (22 residues), see Phobius details amino acids 364 to 384 (21 residues), see Phobius details PF07696: 7TMR-DISMED2" amino acids 32 to 171 (140 residues), 127 bits, see alignment E=9.9e-41 PF07695: 7TMR-DISM_7TM" amino acids 184 to 386 (203 residues), 199.3 bits, see alignment E=1.4e-62 PF00512: HisKA" amino acids 419 to 483 (65 residues), 62 bits, see alignment E=9e-21 PF02518: HATPase_c" amino acids 530 to 643 (114 residues), 67 bits, see alignment E=4e-22

Best Hits

KEGG orthology group: None (inferred from 89% identity to psa:PST_3755)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GIA2 at UniProt or InterPro

Protein Sequence (666 amino acids)

>Psest_0538 Signal transduction histidine kinase (Pseudomonas stutzeri RCH2)
MRYVFLFFLALLPVVTSAVELDEHTRHLPLGQVMQVFEDPLGEARIEDITSTAFESRFQP
HQNAVFNAGYSRSVHWVRVDLNYRPQTVQGARRWLLEVAYPPLDSLQLYLADGQGGYRLA
GDTGDTKPWASREIRQGNYLFEIELQPNQPQRAYLRVASEGSIQVPLSLWSQHAYLEAQP
GRIYVLGMIYGVLLAMLVYNLFIYVSIRDQSYLFYILYIAAFGLYQVSVNGAGVQFLWPD
RPWWANAATPLLIGATGLFGCLFTRSFLRTAEHSRWMDRLLRLIIGFSVVVMVLALTTDY
GLSLRLATALALLFTLAVFAAGILAWLRGMRVARYFIIAWSALLIGGQINTLMVLGHLPH
NFLTMYASQLGAALEVVLLSMALADRINALKDERAKILESARSDLEQLNRELAESNRLKD
EFLSNISHELRTPMMGVMGALELLPASETPEELQQYQHIATGSARDMMRLVNNILVLSEL
RAGKLRLQDQRFSLRETAARLHQQFAPLAREKGLAFDLDFDEQLPDRVYGDAEKLEQCIC
HLLDNAVKFTARGAVNLRFTGAVEPRQLQLNVEVIDSGIGFSDADQAFLYHQFRQVDGSM
TRRYGGLGIGLAISRGLIELLGGRLEQQSRPGLGSRFGIHLRFALNPSDGPASDSSSAVP
PSAPIA