Protein Info for HP15_495 in Marinobacter adhaerens HP15

Annotation: transcription antitermination protein NusB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 158 TIGR01951: transcription antitermination factor NusB" amino acids 22 to 147 (126 residues), 135.9 bits, see alignment E=5e-44 PF01029: NusB" amino acids 23 to 146 (124 residues), 112.7 bits, see alignment E=8.5e-37

Best Hits

Swiss-Prot: 90% identical to NUSB_MARHV: Transcription antitermination protein NusB (nusB) from Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)

KEGG orthology group: K03625, N utilization substance protein B (inferred from 90% identity to maq:Maqu_0846)

Predicted SEED Role

"Transcription termination protein NusB" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PNE1 at UniProt or InterPro

Protein Sequence (158 amino acids)

>HP15_495 transcription antitermination protein NusB (Marinobacter adhaerens HP15)
MSETEGTSPQPAPSGQPKAGDRRRARALAMQGLYQRHFSKTAISDIEAEFMVDNDMSKVD
LLYFRDLLRGVHREQGELDKLIEPFLDRPIKEVDPVELAIVRLGAYELKHRLDVPYKVVI
NEGIEMAKRFGGTEGHKFVNSILDKLSGRLRLAETRAR