Protein Info for Psest_0488 in Pseudomonas stutzeri RCH2

Annotation: Uncharacterized membrane protein affecting hemolysin expression

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 transmembrane" amino acids 27 to 50 (24 residues), see Phobius details amino acids 163 to 187 (25 residues), see Phobius details PF10144: SMP_2" amino acids 35 to 158 (124 residues), 33.4 bits, see alignment E=1.8e-12

Best Hits

KEGG orthology group: None (inferred from 89% identity to psa:PST_3804)

Predicted SEED Role

"HAMP domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GI63 at UniProt or InterPro

Protein Sequence (510 amino acids)

>Psest_0488 Uncharacterized membrane protein affecting hemolysin expression (Pseudomonas stutzeri RCH2)
MNRPASVKPDNFFLMLYRAARQHRVPLVLRIAAHTLLLVALALVIYAWVIGMQFKHAMEQ
QADALGQSLITQTAASATDLLVANDILSLNVLLSNLVKNPLVAHAAIYSVDNRVLAESGT
RPQQGLLGDDSGLYSTPISFQEVIAGHLRVSLDMQQFQQPMTISLQSMGLLSLILLALTL
ILSLRLGRQLATPLMQLRLWLRDPDDPAPGAGRQDEIGDLARQLQARLVPEKPEPELDLS
DALEDDYFEQDDDRGSSEPSFAKQPDRFDIELDEQPQRPPRFSANPDDDDLEMLDDEVAF
DTSPLSSSAVPAPKPAQPTRSAVLAIQLGGQEQLRRLPRPRLTELLQRYRDCLQQAATLY
QAELHTLNDGSSLMLFHSQDDEQNYLTHAICCGELMRALGHALQIDVADIGISLQLQLGL
TQGDNLFDLSQGDLLLSEPAQAALEMSLHSRNLLLVERSISDDRLIQQRARIRPIASPEG
ACCVERLLDPYPSLLERQLARMHELRSRAL