Protein Info for HP15_p187g75 in Marinobacter adhaerens HP15

Annotation: peptidase S8 and S53, subtilisin, kexin, sedolisin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF05922: Inhibitor_I9" amino acids 57 to 128 (72 residues), 24.2 bits, see alignment E=4.4e-09 PF00082: Peptidase_S8" amino acids 165 to 425 (261 residues), 159.1 bits, see alignment E=1.5e-50

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PS37 at UniProt or InterPro

Protein Sequence (447 amino acids)

>HP15_p187g75 peptidase S8 and S53, subtilisin, kexin, sedolisin (Marinobacter adhaerens HP15)
MNIAFKTMVPASCLAAVLAATPLSAHAGLFSSLFSKPAPVPVEETTRDAVSVMEQRYIVT
LAPNVNRILNITDGVQAALDRLLTAVGGGRILFVYENVMQGATVQLTERQARLLESLPGV
LSVEQDSWMSAVNTQTQQDATWGLDRVDQVTLPLDSQYTYPAVSGEGVNVYVLDTGIRTD
HVDFQGRASGVNFHDDSGLAGGGGGGIPLLGDLLGLLFGGLIPFSDEEAISAYSAEDCNG
HGTHVASTATGTLFGVAKQSQVVGLRVLGCNGSGATSAIIEALDWLVVNAEYPAVANMSL
GGGNSQALDNAVREVVSAGIPVVVAAGNSDASACGGSPNRVEEAITVGATDRRDRRSSFS
NHGECVDIMAPGSSITAAWHTGDMDFNTISGTSMASPHVAGAAALLLSEDPSMTPEQVAE
ALISQGSSNQLTDLKGSPNLLLNISPQ