Protein Info for PGA1_c04400 in Phaeobacter inhibens DSM 17395

Annotation: mechanosensitive ion channel-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 789 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 137 to 158 (22 residues), see Phobius details amino acids 190 to 215 (26 residues), see Phobius details amino acids 227 to 247 (21 residues), see Phobius details amino acids 268 to 289 (22 residues), see Phobius details amino acids 299 to 320 (22 residues), see Phobius details amino acids 340 to 362 (23 residues), see Phobius details amino acids 380 to 400 (21 residues), see Phobius details amino acids 448 to 468 (21 residues), see Phobius details amino acids 483 to 502 (20 residues), see Phobius details amino acids 538 to 557 (20 residues), see Phobius details amino acids 565 to 585 (21 residues), see Phobius details PF21088: MS_channel_1st" amino acids 543 to 582 (40 residues), 30.1 bits, see alignment 5.9e-11 PF00924: MS_channel_2nd" amino acids 583 to 648 (66 residues), 52.9 bits, see alignment E=4.7e-18 PF21082: MS_channel_3rd" amino acids 657 to 741 (85 residues), 37.5 bits, see alignment E=4e-13

Best Hits

KEGG orthology group: None (inferred from 69% identity to sit:TM1040_3687)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DXJ1 at UniProt or InterPro

Protein Sequence (789 amino acids)

>PGA1_c04400 mechanosensitive ion channel-like protein (Phaeobacter inhibens DSM 17395)
MVTNSEVVRMRRLVSQFLICLILALAFAVSGTSETLAQGTNSTSGDDLAKAIEQAADSGV
GVIIVDGRGQLVSPSDTPADGTPVPATDQMDGASALMKAQSEVEQFGAALESRLEAMPYS
IFEVQYILRQTSPDGRIITYVKVLGWSLLLLFIGRWVSVEIYGKRIAKKHVVARIKENPE
GYQDKMPFLVFRFLMGVVGTIVAMAFALLTSYLIFGSSGNSSVKFTVTAIYTAFFLSRSV
SDLWRMVLSPYLSQYRIPVFSDRDARRLYVWASVLATYDICSVLFATWVGDFGLNYNVYA
LVYGVLALVGTVGNLLMVVINARAISNAIRAGRPPEACSWLVRLLSVVWAPVLVIYIIFG
WLELAFDLVLERDMSLPLMAGSYSVLTSILVVYGIINYVIERFFNRSQRRVLVESGPISD
EDDADYEGDEAEIAPKPRHPIATFEDLARRIAGILAFTVGFFAMVAIWNPEAAWMENSRL
DRMSDIIVILFIGYIVYHIARIWIDSKIDEEVGDMPVGELGDEGGAGGASRLATLLPLFR
GAILAVVVVSIILIVLLELGINVSPLFAGAGVVGLAVGFGSQTLVRDIFSGAFFLVDDAF
RKGEYIDIGDVKGTVERISVRSFQLRHHLGALHTIPFGEIRVLTNYSRDWVMMKLPLRVT
YDTDVEKVRKLIKKLGQELLDDPVIGDTFIQPLKSQGVIEMQDSAMIIRVKFMTKPGDQW
LVRKKVFQEIRDLFAQEGIKFAHREVTVRLAEDQADQAPKEKRDLAVGAVQAAIDEDLMD
VNDGGGDDR