Protein Info for Psest_4337 in Pseudomonas stutzeri RCH2

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 830 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details PF07660: STN" amino acids 72 to 120 (49 residues), 29.4 bits, see alignment 8.7e-11 PF07715: Plug" amino acids 165 to 270 (106 residues), 82.2 bits, see alignment E=5.8e-27 TIGR01783: TonB-dependent siderophore receptor" amino acids 167 to 830 (664 residues), 460 bits, see alignment E=7.9e-142 PF00593: TonB_dep_Rec_b-barrel" amino acids 344 to 799 (456 residues), 223 bits, see alignment E=2.2e-69

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 57% identity to pau:PA14_32740)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GS21 at UniProt or InterPro

Protein Sequence (830 amino acids)

>Psest_4337 TonB-dependent siderophore receptor (Pseudomonas stutzeri RCH2)
MRSTALPFSPNRSRALALGIRAALLCLPLASVLPAAALAQSAIQQAVRSYDIPAGPLSSA
LSRFAGEAGVLLSVDGSLLQDLQSKGLQGQFGVDDGFAALLQGSGLQAVRDSQGNYSLSR
RTEQSGAVELQPMTVEGFALGNALGSMEGYNATHSSVATKTSMPLAETSQTVSVVTRQQI
EDQGSRSIAQAVRYTPGLMSTPYGATTRYDYVAMRGITDGSVDNLYLDGQKLLGDSGTYS
SLQVDPYFIERIDILKGPSSVLYGRSLPGGLVAMTSKKPQKEASRQLQFSYGSHDYKQAA
FDFTGPLDDERISYRLVGVAKDADTQVDGIEEQRYAVMPSVSIDFTDDTRLTLLAMLQRD
PESGYHGGLPADGTVTSHNGQRISRSFFEGDEDYEKFERDQQMIGYQLEHRFNDVVSARQ
NFQYLDSTVDSGQVYQYGYVAPGSDELVRYYTGADEALHAWTIDNQLQFLFDTGALSHTL
VTGLDYQRRKAKVVYDAAYGLPSVNPYSGAVGAGSPVFYHQYDETRELEQTGLYVQDLIS
LDNWRFSLGVRQDWVDVSFDHTNDASYGDQSDSAKLEQFTGRVGVLYAFDNGLSPYASYS
ESFNPNATAAYNANGSGGFDITLLDPTEGEQYEVGVKYQPLGTDDLYTISYFDLKQSNLA
NKDSNENFYRAVGELTSKGVEVEARLRPIEQVNLIASYTYMDVEYSKDFTGAAGVNNRGN
TPNAVARNMASLWTDYTFDQGPLAGLQVGGGARYFGKSWADAENTLRIPSYTLYDAMLGY
DLSRVGLQGVGVRLNLNNLTDEKYVAACNSLSQCYYGESRNVMATVTYDF