Protein Info for Psest_4297 in Pseudomonas stutzeri RCH2

Annotation: PAS domain S-box

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 803 TIGR00229: PAS domain S-box protein" amino acids 180 to 315 (136 residues), 37.4 bits, see alignment E=1.2e-13 amino acids 342 to 441 (100 residues), 26.6 bits, see alignment E=2.7e-10 amino acids 444 to 571 (128 residues), 27.1 bits, see alignment E=1.9e-10 PF13188: PAS_8" amino acids 183 to 226 (44 residues), 27.3 bits, see alignment 1.1e-09 amino acids 449 to 492 (44 residues), 14.9 bits, see alignment 9.5e-06 PF00989: PAS" amino acids 184 to 305 (122 residues), 36 bits, see alignment E=2.8e-12 PF08448: PAS_4" amino acids 187 to 308 (122 residues), 26.1 bits, see alignment E=3.9e-09 amino acids 344 to 436 (93 residues), 23.2 bits, see alignment E=3e-08 amino acids 453 to 568 (116 residues), 40.2 bits, see alignment E=1.7e-13 PF13426: PAS_9" amino acids 192 to 307 (116 residues), 35.3 bits, see alignment E=5.4e-12 amino acids 343 to 433 (91 residues), 16.6 bits, see alignment E=3.6e-06 amino acids 459 to 565 (107 residues), 15.8 bits, see alignment E=6.2e-06 PF08447: PAS_3" amino acids 344 to 428 (85 residues), 43.8 bits, see alignment E=1.2e-14 PF00512: HisKA" amino acids 573 to 640 (68 residues), 61.3 bits, see alignment E=3.2e-20 PF02518: HATPase_c" amino acids 686 to 795 (110 residues), 110.7 bits, see alignment E=2.4e-35

Best Hits

KEGG orthology group: None (inferred from 86% identity to psa:PST_0054)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GRX6 at UniProt or InterPro

Protein Sequence (803 amino acids)

>Psest_4297 PAS domain S-box (Pseudomonas stutzeri RCH2)
MELPQANPASTLPMTPVRELSRLAALLRYEILDTPEESAFDDFTELAARLCETPIALISL
VDDRRQWFKSRVGLEVSETPREISFCTYTILGEEIFEVPDALQDPRFCHNPLVVGDPHIR
FYAGTPLTSPDGYNLGTLCVIDREPRRLSAEQRDTLERLGRQVIRLFEQHLLAHRYAEQA
ALQQAMLDSASSAVLVTRPDGVVTSVNPTAERMLGHSEQELVGHQLTSALFRREALQRRA
TLLANELQTPIEPDFAVLTAPLHRGRREMSEWRLRHRSGADVPVLVGVTAIHDEQEELRG
YLVNAYDLAYQEQLQLRLQQIAAQVPGMLFQFHWRPDGASCFPYVSEGVEQIYGLSPGQL
AGSFAPIIARVYALDRSALLGSIREAAAELAPWHIEHRVEHPRKGLIWVEARATPLQQVD
GSVLWHGFVTDITVRKAEQLELERQQEMNRRLLEALSEAVIACDADGCLTLFNEKAKQWH
GTDVAPVPPDEWPTRYQLYHPDGVTPLRPEEIPLLRALHGEHVCDHEMVLLGQGEPRHVL
SNADPLYTSDGQPMGAVAVLHDITERKRIERLQREFISTVSHELRTPLTSITGALGLICS
NVMGEVPEAMHELLDIAQQNSQRLNALIDDLLDMDKLHAGKMRFALLRQPLQPQLELALR
SNRNYAEQHGVVLQLGACPAVTVEIDAMRLQQVLSNLLSNAAKFSPAGEQVELSATLSDG
RVRISVRDRGPGISADFRERVFQKFAQADSSDSRQQGGTGLGLAISKELIERMGGQIGFE
SEPGHGACFWFELPSEGLAKESP