Protein Info for Psest_4295 in Pseudomonas stutzeri RCH2

Annotation: PAS domain S-box

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 986 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 332 to 351 (20 residues), see Phobius details PF14827: dCache_3" amino acids 101 to 237 (137 residues), 26.1 bits, see alignment E=2.7e-09 PF08447: PAS_3" amino acids 402 to 487 (86 residues), 37.5 bits, see alignment E=9.3e-13 amino acids 533 to 607 (75 residues), 44.4 bits, see alignment 6.8e-15 TIGR00229: PAS domain S-box protein" amino acids 630 to 754 (125 residues), 104.9 bits, see alignment E=1.7e-34 PF13188: PAS_8" amino acids 634 to 686 (53 residues), 29.3 bits, see alignment 2.5e-10 PF00989: PAS" amino acids 637 to 746 (110 residues), 69.4 bits, see alignment E=1.1e-22 PF08448: PAS_4" amino acids 639 to 751 (113 residues), 42.7 bits, see alignment E=2.3e-14 PF13426: PAS_9" amino acids 644 to 748 (105 residues), 55.5 bits, see alignment E=2.5e-18 PF00512: HisKA" amino acids 755 to 821 (67 residues), 57.2 bits, see alignment 5.9e-19 PF02518: HATPase_c" amino acids 869 to 978 (110 residues), 107.1 bits, see alignment E=2.8e-34

Best Hits

KEGG orthology group: None (inferred from 82% identity to psa:PST_0056)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GTY6 at UniProt or InterPro

Protein Sequence (986 amino acids)

>Psest_4295 PAS domain S-box (Pseudomonas stutzeri RCH2)
MNNVGTTPHWTFALGSLLLVLLFGSLAFNDYRARDAAWQLEIETHGELQSLALRSAQSNQ
QRQADMVASALAGNVEVQRQMRRIDSALRAGATLDDARIELARQRLQAALTPAWSSMQRY
QGMQLQLFWGDSGLTLLRMQQPERFGDAQAARRPMLQQALRDGVMQTGVEVDLRGASSRA
IVPLYAEDERAGEPIGALEVGYNVLPDLAELSDQLAAGLALVVNRAALQAAGLDAPSGVQ
LHSGSDWRLTGHSATQILHWAQAGMLPEPESGMVLRLLSADGRIYMLNQIPLPTDNQARP
TPAPLAVALVWRDISSMQAEHQRAERRLLVKWSLAWFIAEALLLTLAFLLLRRLSVQRQH
RFAQQQQSRRQQRLYDRAQKIASLLPGMVFQLKRFANGRYAFIYVSEGARELYGTDPQRL
LDDAAQALCRVHPQDLSRLKLALLRLAARPGTGAVQFRIYHPQRGLLWAEGRATAERLPD
GSVLWHGFVTEITELMETTRALQKSESRFRAMVGNLPGVVYRCRNDGERNMSYLSNGIER
LTGYPASDFVGDPVRSYASLIHPDDLALARQHPEQDSFEGIYRLINAEGRTVFVRERARV
LHERDDPIGWCDGFIWDVTDQALAKAEMLERERYLSMLLDNVIDAIIIIDARGIIETFNH
AAEQMFGYSSAEVLGQNLSMLMPEPDRSAHDGYLDHYTQRGTSRALEQNRELTALRRNGD
TFTIELRVSQISHHGERKFIGLVRDITERKRIERMKSELVSIVSHELRTPLTSISGALGL
IVGGALGEPSPSMRQMLDIAHQNSLRLGRLVDDLLDMDKLVAGKMALALRAHSLQVQLQL
AVGANQGYAAQHRVQLELLPTPSLQLMADDDRLQQVLANLISNAVKFSPQDGTVRLGGER
RGDWVRIWVRDQGPGIAPEFRARIFQKFSQADSSDTRQKGGTGLGLAISKELIEHMHGRI
GFDSEPGHGACFWCELPLVPAAAELS