Protein Info for Psest_4130 in Pseudomonas stutzeri RCH2

Annotation: uncharacterized domain HDIG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 PF11871: DUF3391" amino acids 3 to 132 (130 residues), 119.1 bits, see alignment E=4.2e-38 PF13487: HD_5" amino acids 158 to 317 (160 residues), 110.9 bits, see alignment E=1.1e-35 TIGR00277: HDIG domain" amino acids 161 to 255 (95 residues), 34 bits, see alignment E=1e-12 PF01966: HD" amino acids 163 to 286 (124 residues), 52.4 bits, see alignment E=1.3e-17

Best Hits

Swiss-Prot: 55% identical to CDPD1_PSEAE: Cyclic di-GMP phosphodiesterase PA4108 (PA4108) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 84% identity to psa:PST_0152)

Predicted SEED Role

"HDIG domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GT91 at UniProt or InterPro

Protein Sequence (404 amino acids)

>Psest_4130 uncharacterized domain HDIG (Pseudomonas stutzeri RCH2)
MLRKVLVSQLRFGMYVHALEGSWFDHPFWRSKFLLTDPADLQALHASGIKAVWIDAGRGV
DVETATPPAAEAPLLGADTIPVVSISVTPPTQQCSAREEMQRATALLKRSREQVTLLFNE
ARLGKAVDPQQCQPLVEQISASLARNGSALLSLARLKTKDEYTYMHSVAVCALMVALARQ
LGLPEDQVHEAGMAGLLHDIGKMAMPLDVLNKPGKLSDDEYMVMRSHPERGHAMLLAAQT
AVSDAVLDVCLHHHEKVNGTGYPHRLEGEQISRLARMGAICDVYDAITSNRPYKTAWDAS
GSLARMAQWHGHFDTQLLHAFVRTVGIYPLGSLVRLQSGRLGVVTEHHPQQLTAPRVKLF
YSTRARAAIVPVEMDLSNPQCGDRIVGREDPAAWGFTNLDALWT