Protein Info for HP15_3905 in Marinobacter adhaerens HP15

Annotation: lipoprotein, YaeC family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF03180: Lipoprotein_9" amino acids 25 to 260 (236 residues), 336.5 bits, see alignment E=3.4e-105

Best Hits

Swiss-Prot: 47% identical to METQ_SALTI: D-methionine-binding lipoprotein MetQ (metQ) from Salmonella typhi

KEGG orthology group: K02073, D-methionine transport system substrate-binding protein (inferred from 95% identity to maq:Maqu_0253)

Predicted SEED Role

"Methionine ABC transporter substrate-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation or Staphylococcal pathogenicity islands SaPI

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PJV9 at UniProt or InterPro

Protein Sequence (260 amino acids)

>HP15_3905 lipoprotein, YaeC family (Marinobacter adhaerens HP15)
MNLKKTLAALAAAATFSGAVAAEELSVAATPVPHAEILEFVKPQLAEQGVELDVKVFTDY
IQPNIQVDQKRMDANFFQHQPYLDEFNEGRGTNLVTVTGVHVEPFGAYSSKIESLDELKE
GAVVAIPNDPTNGGRALLLLQKAGVITLKDESKITATPRDIADNPKDLDFKELEAATLPR
ILNQVDLALINTNYALEAGLNPSEDALVIEGSESPYVNILVARPDNKDSEAMQKLAAALK
SDAVRDFIMEKYEGAVVPAF