Protein Info for Psest_4005 in Pseudomonas stutzeri RCH2
Annotation: Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02454, general secretion pathway protein E (inferred from 97% identity to psa:PST_0270)Predicted SEED Role
"Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0GT69 at UniProt or InterPro
Protein Sequence (594 amino acids)
>Psest_4005 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB (Pseudomonas stutzeri RCH2) MSVLNAPAQDRPLDLNDLLRELVAQGRVAQDSAEQCLTVRRSAVANQQHPLEFLAAQQLD DLQRPGKKLDLETLTVWLAERAGQPYLRIDPLKIDVAAVTPLMSYAFAQRHSILAVAVDS SAVTIASSQPFMHGWEANLTHVLKRPIKRVVANPSDIQRFTVEFYRLAKSVSGASGTDQK ISGAGNFEQLLNLGASDQEPDANDSHIVNIVDWLFQYAFQQRASDIHIEPRREQGSVRFR IDGVLHNVYQFPPQVTMAVVSRLKSLGRMNVAEKRKPQDGRVKTKTPDGGEVELRLSTLP TAFGEKMVMRIFDPEVLLKGFDQLGFSADDLRRWQSMTSQPNGIILVTGPTGSGKTTTLY TTLKQLATPEVNVCTIEDPIEMIEGAFNQMQVQHNIELTFASGVRALMRQDPDIIMVGEI RDLETAEMAIQAALTGHLVLSTLHTNDAPSAITRLLELGVPHYLLKATLLGVMAQRLVRT LCPHCKAPMQLDADDWSALTKPWNAPLPTTAQQAVGCLECRDTGFRGRAGVYEIMLLNDA IKPLITADTDIVALRRQAFKDGMRSLRLSGAQKIAAGLTTVEEVLRVTPQSEQK